Skip to main content
SpringerLink
Log in

A New Phenolic Glycoside from Polygonatum Sibiricum and its α-Glucosidase Inhibitory Activity

  • Published:
Chemistry of Natural Compounds Aims and scope

A new phenolic glycoside 1, together with two known compounds (2, 3), has been isolated from the ethanolic extract of Polygonatum sibiricum F. Delaroche. Its structure was elucidated as (2R)-syringylpropane-1,3-diol-1-O-β-D-glucopyranoside by spectroscopic data (1H NMR, 13C NMR, HSQC, HMBC, and HR-ESI-MS) and chemical evidence. In the in vitro assay, compound 1 displayed potent inhibitory activity against α-glucosidase with an IC50 value of 10.90 μM.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.

Similar content being viewed by others

References

  1. X. S. Shu, J. H. Lv, J. Tao, G. M. Li, H. D. Li, and N. Ma, J. Ethnopharmacol., 124, 539 (2009).

    Article  CAS  Google Scholar 

  2. K. Yelithao, U. Surayot, J. H. Lee, and S. G. You, Prev. Nutr. Food Sci., 21, 245 (2016).

    Article  CAS  Google Scholar 

  3. Y. Zhou, R. L. Wang, Q. M. Chen, and X. Gao, J. Tianjin Med. Univ., 10, 10 (2004).

    Google Scholar 

  4. P. Zhao, C. C. Zhao, X. Li, Q. Z. Gao, L. Q. Huang, P. G. Xiao, and W. Y. Gao, J. Ethnopharmacol., 214, 274 (2018).

    Article  CAS  Google Scholar 

  5. J. H. Shao, J. Chen, C. C. Zhao, J. Shen, W. Y. Liu, W. Y. Gu, and K. H. Li, Nat. Prod. Res., 33, 2662 (2019).

    Article  CAS  Google Scholar 

  6. M. You, J. Xiong, Y. Zhao, L. Cao, S. B. Wu, G. Xia, and J. F. Hu, Planta Med., 77, 1939 (2011).

    Article  CAS  Google Scholar 

  7. C. Yan, Y. Wang, and X. J. Hao, China J. Chin. Mater. Med., 34, 2895 (2009).

    CAS  Google Scholar 

  8. Y. Q. Li, A. Yili, Y. Q. Liu, A. Kawuli, and H. A. Aisa, Chem. Nat. Compd., 50, 352 (2014).

    Article  CAS  Google Scholar 

  9. G. E. Yang, W. Li, C. Huang, L. Lin, Q. B. Zhang, and K. Koike, Chem. Nat. Compd., 46, 876 (2011).

    Article  CAS  Google Scholar 

Download references

Acknowledgment

This work was supported by the National Natural Science Foundation of China (No. 31201563).

Author information

Authors and Affiliations

  1. Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for Modern Production Technology of Grain Crops, Yangzhou University, Yangzhou, P. R. China

    Zi-Yan Chen, Yang Liu, Yu-Qian Zhang, Jian-Hua Shao & Chun-Chao Zhao

  2. Department of Stomatology, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, P. R. China

    Jin-Hua Huang

  3. Jiangxi Shunfutang Chinese Medicinal Decoction Pieces Co., Ltd., Nanchang, P. R. China

    Ji-Zhou Zhu

Authors
  1. Zi-Yan Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yang Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yu-Qian Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jin-Hua Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jian-Hua Shao
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ji-Zhou Zhu
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Chun-Chao Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Chun-Chao Zhao.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2021, pp. 43–44.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, ZY., Liu, Y., Zhang, YQ. et al. A New Phenolic Glycoside from Polygonatum Sibiricum and its α-Glucosidase Inhibitory Activity. Chem Nat Compd 57, 50–52 (2021). https://doi.org/10.1007/s10600-021-03279-0

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-021-03279-0

Keywords

Search

Navigation