A new chromene derivative, alternapyran (1), along with three known compounds (2–4), was isolated from the Alternaria sp. ZG22 obtained from a Dasymaschalon rostratum collected from the Hainan. The structure of the new compound 1 was elucidated by NMR and mass spectroscopic data. Compounds 2 and 3 showed broad spectrum antibacterial activity against four terrestrial pathogenic bacteria.
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M. Sathiyabama and R. Parthasarathy, Nat. Prod. Res.,32, 1573 (2018).
S. S. Xie, Y. Wu, Y. B. Qiao, Y. Guo, J. P. Wang, Z. X. Hu, Q. Zhang, X. X. Li, J. F. Huang, and Q. Zhou, J. Nat. Prod., 81, 1311 (2018).
W. J. Wang, J. J. Gong, X. R. Liu, C. Dai, Y. Y. Wang, X. N. Li, J. P. Wang, Z. W. Luo, Y. Zhou, Y. B. Xue, H. C. Zhu, C. M. Chen, and Y. H. Zhang, J. Nat. Prod., 81, 1578 (2018).
B. P. Bashyal, B. P. Wellensiek, R. Ramakrishnan, S. Faeth, N. Ahmad, and A. Gunatilaka, Bioorg. Med. Chem., 22, 6112 (2014).
B. P. Bashyal, E. M. Wijeratne, J. Tillotson, A. E. Arnold, E. Chapman, and A. A. Gunatilaka, J. Nat. Prod.,80, 427 (2017).
H. Ding, D. S. Zhang, B. Z. J. Zhou, and Z. J. Ma, Mar. Drugs,15, 76 (2017).
A. Idris, M. A. Tantry, B. A. Ganai, A. N. Kamili, and J. S. Williamson, Phytochem. Lett., 11, 264 (2015).
J. Tian, L. Y. Fu, Z. H. Zhang, X. J. Dong, D. Xu, Z. L. Mao, Y. Liu, D. W. Lai, and L. G. Zhou, Nat. Prod. Res., 31, 387 (2017).
H. Laatsch, Tetrahedron Lett., 37, 3287 (1976).
C. W. Chang, H. S. Chang, M. J. Cheng, T. W. Liu, S. Y. Hsieh, G. F. Yuan, and I. S. Chen, Chem. Biodiv.,11, 949 (2014).
A. K. Nadeau and J. L. Sorensen, Tetrahedron Lett., 52, 1697 (2011).
S. J. Pastine, S. W. Youn, and D. Sames, Org. Lett., 5, 1055 (2003).
C. G. Pierce, P. Uppuluri, A. R. Tristan, F. L. Wormley, E. Mowat, G. Ramage, and J. L. Lopez-Ribot, Nat. Protoc.,3, 1494 (2008).
This work was supported by the Key Research and Development Project of Hainan Province (ZDYF2018164); the Scientific research Project of Hainan Province colleges and universities (Hnky2017-87); the Undergraduate Innovation and Entrepreneurship Training Program (cxcyxj2018008, cxcyxj2018010); the Natural Science Foundation of Hainan Province (218QN234); the Innovative Research Team Project of the Ministry (IRT-16R19); the Special projects of the central government for the development of local science and technology (ZY2018HN07); the National Natural Science Foundation of China (21362009, 81360478); International S&T cooperation Program of China (ISTCP) (2014DFA40850).
Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2020, pp. 355–356.
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Song, X., Luo, J., Li, Y. et al. A New Chromene Derivative from Alternaria sp. ZG22. Chem Nat Compd 56, 409–411 (2020). https://doi.org/10.1007/s10600-020-03049-4
- Alternaria sp.
- antibacterial activity