New Fatty Acid Derivative from the Stem Bark of Cassia grandis

For the first time, the n-hexane extract from the dried stem bark of Cassia grandis L.f. was investigated, and one new fatty acid derivative, named casgraester A (1), was obtained, together with three known ones, 2,3-dihydroxypropyl 28-hydroxyoctacosanoate (2), 2,3-dihydroxypropyl octacosanoate (3), bis-(2,3-dihydroxypropyl)tetracosanedioate (4), three known triterpenoids, lupeol (5), betulinic acid (6), oleanolic acid (7), and three known steroids, β-sitosterol (8), 3-O-β-D-glucopyranosyl-β-sitosterol (9), and 3-O-β-D-glucopyranosylbrassicasterol (10). For the first time, compounds 2–4, 6, and 10 were reported from the genus Cassia, while compounds 5, 7, and 9 were found for the first time from this species. Their structures were elucidated by IR, HR-ICR-MS, ESI-MS/MS, and NMR experiments.

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References

  1. 1.

    T. L. Do, Medicinal Plants and Remedy of Vietnam, Publisher of Medicine, Hanoi, Vietnam, 2004.

    Google Scholar 

  2. 2.

    E. Valencia, A. Madinaveitia, J. Bermejo, and M. P. Gupta, Fitoterapia, 66, 476 (1995).

    CAS  Google Scholar 

  3. 3.

    T. N. Ngo, C. T. Vo, N. K. T. Pham, N. M. Phan, T. D. Bui, Q. L. Ngo, V. S. Dang, C. L. Tran, D. T. Mai, and T.P. Nguyen, Nat. Prod. Res., 33, 174 (2019).

    CAS  Article  Google Scholar 

  4. 4.

    T. P. Nguyen, T. D. Le, N. M. Phan, T. D. Bui, N. K. T. Pham, T. M. L. Do, D. T. Nguyen, and D. T. Mai, Nat. Prod. Res., 30, 2389 (2016).

    CAS  Article  Google Scholar 

  5. 5.

    T. P. Nguyen, D. T. Mai, T. H. T. Do, and N. M. Phan, Nat. Prod. Commun., 12, 1061 (2017).

    Google Scholar 

  6. 6.

    T. P. Nguyen, N. M. Phan, T. D. Bui, T. D. Le, N. M. A. Tran, T. N. T. Pham, and D. T. Mai, Nat. Prod. Res., 31, 2281 (2017).

    CAS  Article  Google Scholar 

  7. 7.

    T. P. Nguyen, C. L. Tran, C. H. Vuong, T. H. T. Do, T. D. Le, D. T. Mai, and N. M. Phan, Nat. Prod. Res., 31, 2587 (2017).

    CAS  Article  Google Scholar 

  8. 8.

    T. P. Nguyen, T. T. V. Tran, D. T. Mai, T. D. Le, N. M. Phan, and T. D. Bui, Nat. Prod. Res., 29, 1432 (2015).

    CAS  Article  Google Scholar 

  9. 9.

    P. T. N. Trinh, N. Q. Luan, M. D. Tri, V. D. Khanh, N. H. An, P. N. Minh, P. N. An, N. T. L. Thuy, N. K. P. Phung, and L. T. Dung, Nat. Prod. Res., 31, 1733 (2017).

    CAS  Article  Google Scholar 

  10. 10.

    C. D. R. Jose, P. Pipijn, and G. Ana, J. Cereal Sci., 58, 248 (2013).

    Article  Google Scholar 

  11. 11.

    N. Y. Yang, W. W. Tao, and J. A. Duan, J. Chem. Res., 7, 423 (2009).

    Article  Google Scholar 

  12. 12.

    A. K. Jamal, W. A. Yaacob, and L. B. Din, J. Phys. Sci., 19, 45 (2008).

    CAS  Google Scholar 

  13. 13.

    D. Ghias, B. S. S. Waliullah, A. Muhammad, S. Anwar, A. Ashfaq, and U. Ala, Middle-East J. Sci. Res., 8, 85 (2011).

    Google Scholar 

  14. 14.

    W. A. A. Yahya, W. A. Yaacob, and I. Nazlina, Malaysian J. Anal. Sci., 15, 22 (2011).

    Google Scholar 

  15. 15.

    N. L. H. Ton, M. H. Nguyen, and D. L. Tran, Cantho Univ. J. Sci., 19b, 56 (2011) (in Vietnamese).

  16. 16.

    J. Gao, L. Hu, and J. Liu, Steroids, 66, 771 (2001).

    Article  Google Scholar 

  17. 17.

    R. Sacchi, F. Addeo, and L. Paolillo, Magn. Reson. Chem., 35, S133 (1997).

    CAS  Article  Google Scholar 

  18. 18.

    R. K. Mukherjee, Y. Fujimoto, and K. Kakinuma, Phytochemistry, 37, 1641 (1994).

    CAS  Article  Google Scholar 

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Correspondence to Tan Phat Nguyen.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2020, pp. 341–342.

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Ngo, Q.L., Phan, N.M. & Nguyen, T.P. New Fatty Acid Derivative from the Stem Bark of Cassia grandis. Chem Nat Compd 56, 392–394 (2020). https://doi.org/10.1007/s10600-020-03044-9

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Keywords

  • Cassia grandis
  • fatty acid derivative
  • casgraester A
  • 2,3-dihydroxypropyl 28-hydroxyoctacosanoate
  • 2,3-dihydroxypropyl octacosanoate
  • bis-(2,3-dihydroxypropyl)tetracosanedioate