Two new naphthaldehyde derivatives, 2-(hydroxymethyl)-5-methoxy-7-(2-oxopropyl)naphthalene-1-carbaldehyde (1) and 2-(hydroxymethyl)-5-methyl-7-(2-oxopropyl)naphthalene-1-carbaldehyde (2), were isolated from the whole plants of Comastoma pulmonarium. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 showed high anti-TMV activity with inhibition rates of 34.6 and 30.2%, respectively.
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Acknowledgment
This research was supported by the National Natural Science Foundation of China (No. 21562047), the Research Foundation of China Tobacco Company (No. 110201502006), and the Research Foundation of China Tobacco Yunnan Industrial Co., Ltd. (Nos. 2015539200340277 and 2016JC03).
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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2019, pp. 557–559.
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Wang, XL., Li, P., Xiang, HY. et al. Two New Naphthaldehyde Derivatives from Comastoma pulmonarium. Chem Nat Compd 55, 648–650 (2019). https://doi.org/10.1007/s10600-019-02769-6
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DOI: https://doi.org/10.1007/s10600-019-02769-6