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New Fatty Acids from the Leaves of Vernicia fordii

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Chemistry of Natural Compounds Aims and scope

Two new conjugated ketonic fatty acids, (10E,12E)-ethyl 9-oxo-octadeca-10,12-dienoate (1) and (14S)-(10E,12E)-methyl 14-hydroxy-9-oxo-octadeca-10,12-dienoate (2), were isolated from the leaves of Vernicia fordii collected from Hunan Province of China. Their structures were characterized by means of spectroscopic analyses. All of them were tested for their cytotoxicity against five human cancer cell lines.

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References

  1. A. Schonemann and H. G. M. Edwards, Anal. Bioanal. Chem., 400, 1173 (2011).

    Article  CAS  PubMed  Google Scholar 

  2. M. Igarashi and T. Miyazawa, Cancer Lett., 148, 173 (2000).

    Article  CAS  PubMed  Google Scholar 

  3. Y. Ito, S. Yanase, H. Tokuda, M. Kishishita, H. Ohigashi, M. Hirota, and K. Koshimizu, Cancer Lett., 18, 87 (1983).

    Article  CAS  PubMed  Google Scholar 

  4. Y. H. Pei, O. K. Kwon, J. S. Lee, H. J. Cha, K. S. Ahn, S. R. Oh, H. K. Lee, and Y. W. Chin, Chem. Pharm. Bull., 61, 674 (2013).

    Article  CAS  PubMed  Google Scholar 

  5. Y. H. Pei, J. W. Kim, H. B. Kang, H. K. Lee, C. S. Kim, H. H. Song, Y. W. Chin, and S. R. Oh, Bioorg. Med. Chem. Lett., 22, 2318 (2012).

    Article  CAS  PubMed  Google Scholar 

  6. B. I. Fozdar, S. A. Khan, T. Shamsuddin, K. M. Shamsuddin, and J. P. Kintzinger, Phytochemistry, 28, 2459 (1989).

    Article  CAS  Google Scholar 

  7. M. Hirota, H. Ohigashi, and K. Koshimiz, Agric. Biol. Chem., 43, 2523 (1979).

    Google Scholar 

  8. T. Okuda, T. Yoshida, S. Koike, and N. Toh, Phytochemistry, 14, 509 (1975).

    Article  CAS  Google Scholar 

  9. R. G. Binder, T. H. Applewhite, M. J. Diamond, and L. A. Goldblatt, J. Am. Oil Chem. Soc., 41, 108 (1964).

    Article  CAS  Google Scholar 

  10. E. Vioque and R. T. Holman, Arch. Biochem. Biophys., 99, 522 (1962).

    Article  CAS  PubMed  Google Scholar 

  11. T. Hasegawa, M. Ishibashi, T. Takata, F. Takano, and T. Ohta, Chem. Pharm. Bull., 55, 1748 (2007).

    Article  CAS  PubMed  Google Scholar 

  12. J. T. Wu, Y. R. Chiang, W. Y. Huang, and W. N. Jane, Aquat. Toxicol., 80, 338 (2006).

    Article  CAS  PubMed  Google Scholar 

  13. I. Siegel, T. L. Liu, E. Yaghoubzadeh, T. S. Keskey, and N. Gleicher, J. Natl. Cancer Inst., 78, 271 (1987).

    CAS  Google Scholar 

  14. M. Zhou, M. M. Miao, G. Du, X. N. Li, S. Z. Shang, W. Zhao, Z. H. Liu, G. Y. Yang, C. T. Che, Q. F. Hu, and X. M. Gao, Org. Lett., 16, 5016 (2014).

    Article  CAS  PubMed  Google Scholar 

  15. L. J. Reed and H. Muench, Am. J. Epidemiol., 27, 493 (1938).

    Article  Google Scholar 

Download references

Acknowledgment

This study was supported by the Project of Yunnan Provincial Education Department (No. 2015Z115) and China Tobacco Yunnan Industrial Co., Ltd. (2016539200340107).

Supporting information available: 1D and 2D NMR spectra of compounds 1 and 2 are available free of charge via the Internet.

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Correspondence to Yanqing Ye or Gang Du.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2019, pp. 521–523.

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Zhou, M., Xing, H., Zhang, R. et al. New Fatty Acids from the Leaves of Vernicia fordii. Chem Nat Compd 55, 602–605 (2019). https://doi.org/10.1007/s10600-019-02758-9

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  • DOI: https://doi.org/10.1007/s10600-019-02758-9

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