Chemistry of Natural Compounds

, Volume 54, Issue 2, pp 405–406 | Cite as

A Reinvestigation of Norditerpenoid Alkaloids from the Roots of Delphinium formosum

  • B. Sen-Utsukarci
  • J. Zapp
  • A. K. Kiemer
  • A. H. Mericli

There are almost 300 Delphinium species in the world and 32 species in Turkey; 17 of them are endemic in Anatolia. The use of Delphinium L. species against lice and scorpions was already mentioned by Dioscorides. Also, the British army used D. staphisagria L. and D. peregrinum L. powder against lice in the battle of Waterloo. D. staphisagria is known as “mevzek, kokarot, kokarotu, mevezek, and muzudek” in traditional Turkish medicine. The dried and mature seeds of D. staphisagria were used as sedative (in rabies, tetanus, and epilepsy), purgative, and emetic traditionally in Turkey. Its internal use was abandoned because of its high toxicity. The seeds are applied in powder form or as an infusion (1–3%) or ointment to the body or on the head. The toxicity can be seen even in external applications as an insect repellent. The seeds of Consolida orientalis (Gay) Schrod. (Syn: D. ajacis L.) and Consolida regalis S. F. Gray subsp. regalis (Syn: D. consolidaL.) have antiparasitic activity....



The present work was supported by the Research Fund of Istanbul University. Project No. 33641. Burcu Sen thanks the Tincel Vakfi for a fellowship to do a part of this study in Saarbruecken (Germany).


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • B. Sen-Utsukarci
    • 1
  • J. Zapp
    • 2
  • A. K. Kiemer
    • 2
  • A. H. Mericli
    • 3
  1. 1.Istanbul University, Faculty of Pharmacy, Department of PharmacognosyIstanbulTurkey
  2. 2.Saarland University, Department of Pharmacy, Pharmaceutical BiologySaarbrueckenGermany
  3. 3.Near East University, Faculty of Pharmacy, Department of PharmacognosyNicosiaTurkey

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