Advertisement

Chemistry of Natural Compounds

, Volume 54, Issue 2, pp 405–406 | Cite as

A Reinvestigation of Norditerpenoid Alkaloids from the Roots of Delphinium formosum

  • B. Sen-Utsukarci
  • J. Zapp
  • A. K. Kiemer
  • A. H. Mericli
Article
  • 46 Downloads

There are almost 300 Delphinium species in the world and 32 species in Turkey; 17 of them are endemic in Anatolia. The use of Delphinium L. species against lice and scorpions was already mentioned by Dioscorides. Also, the British army used D. staphisagria L. and D. peregrinum L. powder against lice in the battle of Waterloo. D. staphisagria is known as “mevzek, kokarot, kokarotu, mevezek, and muzudek” in traditional Turkish medicine. The dried and mature seeds of D. staphisagria were used as sedative (in rabies, tetanus, and epilepsy), purgative, and emetic traditionally in Turkey. Its internal use was abandoned because of its high toxicity. The seeds are applied in powder form or as an infusion (1–3%) or ointment to the body or on the head. The toxicity can be seen even in external applications as an insect repellent. The seeds of Consolida orientalis (Gay) Schrod. (Syn: D. ajacis L.) and Consolida regalis S. F. Gray subsp. regalis (Syn: D. consolidaL.) have antiparasitic activity....

Notes

Acknowledgment

The present work was supported by the Research Fund of Istanbul University. Project No. 33641. Burcu Sen thanks the Tincel Vakfi for a fellowship to do a part of this study in Saarbruecken (Germany).

References

  1. 1.
    A. Ulubelen, A. H. Mericli, F. Mericli, N. Kilincer, A. G. Ferizli, M. Emekci, and S. W. Pelletier, Phytother. Res., 15, 170 (2001).CrossRefPubMedGoogle Scholar
  2. 2.
    T. Baytop, Turkiye′de Bitkiler Ile Tedavi [2nd ed.]; Nobel Tip Kitapevleri Ltd Sti, Istanbul, 1999, 168 pp.Google Scholar
  3. 3.
    K. Hiller and M. F. Melzig, Lexikon der Arzneipflanzen und Drogen, (3th ed), Area Verlag, Berlin, 2006, 244 pp.Google Scholar
  4. 4.
    F. Mericli, A. H. Mericli, H. Becker, A. Ulubelen, S. Ozden, N. Durust, and M. Tanker, Phytochemistry, 42, 1249 (1996).CrossRefGoogle Scholar
  5. 5.
    M. Tanker and S. Ozden, Ankara Eczacilik Fakultesi Mecmuasi, 5, 113 (1975).CrossRefGoogle Scholar
  6. 6.
    F. Mericli, A. H. Mericli, H. Becker, and A. Ulubelen, Phytochemistry, 42, 1257 (1996).CrossRefGoogle Scholar
  7. 7.
    S. W. Pelletier, R. S. Sawhney, H. K. Desai, and N. V. Mody, J. Nat. Prod., 43, 395 (1980).CrossRefGoogle Scholar
  8. 8.
    S. W. Pelletier, O. D. Jr. Dailey, N. V. Mody, and J. D. Olsen, J. Org. Chem., 46, 3284 (1981).Google Scholar
  9. 9.
    S. W. Pelletier, F. M. Harraz, M. M. Badawi, S. Tantiraksachai, F. Wang, and S. Chen, Heterocycles, 24, 1853 (1986).CrossRefGoogle Scholar
  10. 10.
    S. Chen and X. Hao, Acta Bot. Yunnanica, 8, 86 (1986).Google Scholar
  11. 11.
    E. D. Khairitdinova, E. M. Tsyrlina, L. V. Spirikhin, N. I. Fedorov, and M. S. Yunusov, Chem. Nat. Compd., 41, 575 (2005).CrossRefGoogle Scholar
  12. 12.
    F.-P. Wang and S.W. Pelletier, Acta Bot. Sin., 32, 733 (1990).Google Scholar
  13. 13.
    X.-L. Zhou, Q.-H. Chen, and F.-P. Wang, Chem. Pharm. Bull., 52, 381 (2004).CrossRefPubMedGoogle Scholar
  14. 14.
    S.-H. Jiang, Y.-L. Zhu, Z.-Y. Zhao, and R.-H. Zhu, Acta Pharm. Sin., 18, 440 (1983).Google Scholar
  15. 15.
    O. E. Edwards and M. Przybylska, Can. J. Chem., 60, 2661 (1982).CrossRefGoogle Scholar
  16. 16.
    M. Shamma, P. Chinnasamy, G. A. Miana, A. Khan, M. Bashir, M. Salazar, P. Patil, and J. L. Beal, J. Nat. Prod., 42, 615 (1979).CrossRefPubMedGoogle Scholar
  17. 17.
    G. Wu, S. Jiang, and D. Zhu, Phytochemistry, 42, 1253 (1996).CrossRefGoogle Scholar
  18. 18.
    S. Suzgec, L. Bitis, S. Pirildar, H. Ozcelik, J. Zapp, H. Becker, F. Mericli, and A. H. Mericli, Chem. Nat. Compd, 42, 75 (2006).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • B. Sen-Utsukarci
    • 1
  • J. Zapp
    • 2
  • A. K. Kiemer
    • 2
  • A. H. Mericli
    • 3
  1. 1.Istanbul University, Faculty of Pharmacy, Department of PharmacognosyIstanbulTurkey
  2. 2.Saarland University, Department of Pharmacy, Pharmaceutical BiologySaarbrueckenGermany
  3. 3.Near East University, Faculty of Pharmacy, Department of PharmacognosyNicosiaTurkey

Personalised recommendations