A Reinvestigation of Norditerpenoid Alkaloids from the Roots of Delphinium formosum
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There are almost 300 Delphinium species in the world and 32 species in Turkey; 17 of them are endemic in Anatolia. The use of Delphinium L. species against lice and scorpions was already mentioned by Dioscorides. Also, the British army used D. staphisagria L. and D. peregrinum L. powder against lice in the battle of Waterloo. D. staphisagria is known as “mevzek, kokarot, kokarotu, mevezek, and muzudek” in traditional Turkish medicine. The dried and mature seeds of D. staphisagria were used as sedative (in rabies, tetanus, and epilepsy), purgative, and emetic traditionally in Turkey. Its internal use was abandoned because of its high toxicity. The seeds are applied in powder form or as an infusion (1–3%) or ointment to the body or on the head. The toxicity can be seen even in external applications as an insect repellent. The seeds of Consolida orientalis (Gay) Schrod. (Syn: D. ajacis L.) and Consolida regalis S. F. Gray subsp. regalis (Syn: D. consolidaL.) have antiparasitic activity....
The present work was supported by the Research Fund of Istanbul University. Project No. 33641. Burcu Sen thanks the Tincel Vakfi for a fellowship to do a part of this study in Saarbruecken (Germany).
- 2.T. Baytop, Turkiye′de Bitkiler Ile Tedavi [2nd ed.]; Nobel Tip Kitapevleri Ltd Sti, Istanbul, 1999, 168 pp.Google Scholar
- 3.K. Hiller and M. F. Melzig, Lexikon der Arzneipflanzen und Drogen, (3th ed), Area Verlag, Berlin, 2006, 244 pp.Google Scholar
- 8.S. W. Pelletier, O. D. Jr. Dailey, N. V. Mody, and J. D. Olsen, J. Org. Chem., 46, 3284 (1981).Google Scholar
- 10.S. Chen and X. Hao, Acta Bot. Yunnanica, 8, 86 (1986).Google Scholar
- 12.F.-P. Wang and S.W. Pelletier, Acta Bot. Sin., 32, 733 (1990).Google Scholar
- 14.S.-H. Jiang, Y.-L. Zhu, Z.-Y. Zhao, and R.-H. Zhu, Acta Pharm. Sin., 18, 440 (1983).Google Scholar