Chemical Constituents of Euscaphis japonica
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Euscaphis japonica is a deciduous small tree that grows mainly in the mountains and forests of southeastern central China, northern Taiwan, and southwestern Japan . Previous research found that some compounds from E. japonica showed antifibrotic activity , anticancer , inhibitory activity on lipopolysaccharide-induced nitric oxide production in BV2 microglia , and lipogenesis reducing properties . The EtOH fraction from E. japonica seed showed strong antimicrobic activity against Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae . Its water extracts can alleviate acute alcoholic liver injury . As part of our investigations on plant-derived bioactive chemical constituents [8, 9, 10, 11], E. japonica was chemically studied. Ten compounds were isolated and identified as betulinic acid (1), oleanic acid (2), pomolic acid (3), 3β,23-dihydroxy-urs-12-en-28-oic acid (4), rutundic acid (5), tetraketide (6), β-sitosterol (7), β-sitosterol-3-O-β-D-glucopy...
This work was supported by Grants from National Natural Science Foundation of China (No. 31170701) and Zhejiang Provincial Collaborative Innovation Center of Food Safety and Nutrition (No. 2017SICR110).
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