Chemical Constituents of Euscaphis japonica
- 81 Downloads
Euscaphis japonica is a deciduous small tree that grows mainly in the mountains and forests of southeastern central China, northern Taiwan, and southwestern Japan . Previous research found that some compounds from E. japonica showed antifibrotic activity , anticancer , inhibitory activity on lipopolysaccharide-induced nitric oxide production in BV2 microglia , and lipogenesis reducing properties . The EtOH fraction from E. japonica seed showed strong antimicrobic activity against Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae . Its water extracts can alleviate acute alcoholic liver injury . As part of our investigations on plant-derived bioactive chemical constituents [8, 9, 10, 11], E. japonica was chemically studied. Ten compounds were isolated and identified as betulinic acid (1), oleanic acid (2), pomolic acid (3), 3β,23-dihydroxy-urs-12-en-28-oic acid (4), rutundic acid (5), tetraketide (6), β-sitosterol (7), β-sitosterol-3-O-β-D-glucopy...
This work was supported by Grants from National Natural Science Foundation of China (No. 31170701) and Zhejiang Provincial Collaborative Innovation Center of Food Safety and Nutrition (No. 2017SICR110).
- 1.Editorial Committee for Flora of China, Flora of China, Vol. 11, Science Press, Beijing, 1999, p. 67.Google Scholar
- 6.L. N. Luo, D. B. Xiang, Q. M. Hu, and G. Pei, Chin. Trad. Pat Med., 36 (10), 2215 (2014).Google Scholar
- 7.F. Zhong and H. Gao, J. Huaihua Univ., 30 (2), 29 (2012).Google Scholar
- 12.R. J. Wu, L. Q. Song, L. Tan, Y. Zhan, J. Ruan, and C. Q. Xu, Chin. Trad. Herb. Drugs, 46 (19), 2834 (2015).Google Scholar
- 13.S. H. Wu, Y. B. Ma, X. D. Luo, X. J. Hao, and D. G. Wu, Chin. Trad. Herb. Drugs, 33 (8), 679 (2002).Google Scholar
- 14.P. Liu, H. Q. Duan, Q. Pan, Y. W. Zhang, and Z. Yao, Chin. Trad. Herb. Drugs, 31 (22), 1875 (2006).Google Scholar
- 15.G. B. Xie, S. X. Zhou, L. D. Lei, and P. F. Tu, Chin. J. Chin. Mater. Med., 32 (18), 1890 (2007).Google Scholar
- 17.K. Yuan, W. T. Qiao, and M. W. Yin, Asian J. Chem., 21 (9), 7138 (2009).Google Scholar
- 19.G. F. Shi, H. R. Sun, Y. F. Zhao, X. F. Chen, and Z. G. Qi, Nat. Prod. Res. Dev., 20 (1), 60 (2008).Google Scholar
- 20.D. B. Xiang, Q. M. Hu, Y. Tan, Y. C. Meng, and G. Pei, Chin. Trad. Pat. Med., 37 (4), 793 (2015).Google Scholar
- 22.X. M. Zhu, Y. T. Di, S. L. Peng, M. K. Wang, and L. S. Ding, Chin. Trad. Herb. Drugs, 34 (3), 196 (2003).Google Scholar
- 23.K. H. Lee, K. Tagahara, H. Suzuki, R. Y. Wu, M. Haruna, Iris. Hall, H. C. Huang, K. Ito, T. Iida, and J. S. Lai, J. Nat. Prod., 44 (5), 530 (1981).Google Scholar