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Isolation, Characterization, and Antimicrobial Activity of Extracellular Polypeptides from Diazotrophic Strain Rhizobium radiobacter

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Chemistry of Natural Compounds Aims and scope

Antimicrobial polypeptide fractions were isolated from Rhizobium radiobacter culture medium and purified. Mass-spectrometric analysis showed that the most active biocidal peptide fraction contained 24 components with molecular masses in the range 1171.14–3626.78 Da. The isolated peptide fractions contained 60 and 56% protein, respectively, and inhibited the growth of test pathogens Candida albicans (CA) and Escherichia coli (EC). These polypeptides demonstrated protective properties.

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Acknowledgment

The research was financially supported by the Chinese Program for National Scientific Research (No. U1403201), Key Technology and Application Demonstration of the Production and Value-added Processing of Chickpea (No. 2015 BAD29B03-4). We thank Central Asia Drug Research and Development Center of the Chinese Academy of Sciences, Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing and the Academy of Sciences of the Republic of Uzbekistan for support of the research.

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Authors and Affiliations

  1. Key Laboratory of Plants Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1, Urumqi, 830011, Xinjiang, P. R. China

    P. Rozi, A. Waili, Y. Mijiti, Y. H. Gao, A. Yili & H. A. Aisa

  2. State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, 830011, Urumqi, P. R. China

    A. Yili & H. A. Aisa

  3. University of Chinese Academy of Science, 100039, Beijing, P. R. China

    P. Rozi, A. Waili, Y. Mijiti & Y. H. Gao

  4. Institute of Plant Genetics and Experimental Biology, Academy of Sciences of the Republic of Uzbekistan, Kibraiskii District, Tashkent Oblast, 111226, Uzbekistan

    B. A. Rasulov

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  1. P. Rozi
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  2. B. A. Rasulov
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  3. A. Waili
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  4. Y. Mijiti
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  5. Y. H. Gao
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  6. A. Yili
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  7. H. A. Aisa
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Corresponding author

Correspondence to A. Yili.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2018, pp. 277–280.

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Rozi, P., Rasulov, B.A., Waili, A. et al. Isolation, Characterization, and Antimicrobial Activity of Extracellular Polypeptides from Diazotrophic Strain Rhizobium radiobacter. Chem Nat Compd 54, 330–333 (2018). https://doi.org/10.1007/s10600-018-2334-y

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  • DOI: https://doi.org/10.1007/s10600-018-2334-y

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