Synthesis of Sulfones and Sulfoxides Based on (+)-usnic Acid
- 3 Downloads
Sulfones were produced by meta-chloroperbenzoic-acid oxidation of the corresponding thioethers prepared from (+)-usnic acid. Reaction of the thioethers with H2O2 in the presence of VO(acac)2 formed a mixture of sulfoxide diastereomers. Possible chiral oxidation of the thioethers into sulfoxides was studied.
Keywords(+)-usnic acid thioethers sulfoxidation chiral oxidation sulfones
The work was supported financially by RFBR Project 13-03-00810-a. We thank the Khimiya Center for Collective Use, SB, RAS, for performing the spectral and analytical measurements.
- 5.V. V. Gavrilov, V. A. Startseva, L. E. Nikitina, O. A. Lodochnikova, O. I. Gnezdilov, S. A. Lisovskaya, N. I. Glushko, and E. N. Klimovitskii, Khim.-farm. Zh., 44 (3), 17 (2010).Google Scholar
- 11.E. A. Koneva, K. P. Volcho, D. V. Korchagina, N. I. Komarova, A. I. Kochnev, N. F. Salakhutdinov, and A. G. Tolstikov, Izv. Ross. Akad. Nauk, Ser. Khim., 1, 105 (2008).Google Scholar