Synthesis of Sulfones and Sulfoxides Based on (+)-usnic Acid
Sulfones were produced by meta-chloroperbenzoic-acid oxidation of the corresponding thioethers prepared from (+)-usnic acid. Reaction of the thioethers with H2O2 in the presence of VO(acac)2 formed a mixture of sulfoxide diastereomers. Possible chiral oxidation of the thioethers into sulfoxides was studied.
Keywords(+)-usnic acid thioethers sulfoxidation chiral oxidation sulfones
The work was supported financially by RFBR Project 13-03-00810-a. We thank the Khimiya Center for Collective Use, SB, RAS, for performing the spectral and analytical measurements.
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