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Chemistry of Natural Compounds

, Volume 53, Issue 2, pp 325–327 | Cite as

Axinellin A and B: Two New Pyrrolactam Alkaloids from Axinella sp.

  • Wei-Guo Xu
  • Jiao-Jiao Xu
  • Jia Wang
  • Guo-Sheng Xing
  • Wei Qiao
  • Hong-Quan Duan
  • Chuan Zhao
  • Sheng-An Tang
Article
  • 58 Downloads

Two new pyrrolactam alkaloids, axinelline A (1) and B (2), were isolated from the n-BuOH extract of marine sponge Axinella sp. The structures of these compounds were elucidated on the basis of spectroscopic methods (HR-ESI-MS, 1D and 2D NMR).

Keywords

marine natural products Axinella sp pyrrolactam alkaloids chemical constituents structure identification 

Notes

Acknowledgment

This work was partially supported by the National Natural Science Foundation of China (Grant No. 81102371), Key Program of National Natural Science Foundation of Tianjin (Grant No. 16JCZDJC32600), China Postdoctoral Science Foundation (Grant No. 2016M591399), and the Natural Science Foundation of Tianjin, China (Grant No. 10JCYBJC15000).

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Wei-Guo Xu
    • 1
  • Jiao-Jiao Xu
    • 2
  • Jia Wang
    • 2
  • Guo-Sheng Xing
    • 3
  • Wei Qiao
    • 2
  • Hong-Quan Duan
    • 2
  • Chuan Zhao
    • 2
  • Sheng-An Tang
    • 2
  1. 1.Department of TraumatologyTianjin HospitalTianjinChina
  2. 2.Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of PharmacyTianjin Medical UniversityTianjinChina
  3. 3.Orthopeadic Research Institute of Tianjin HospitalTianjinChina

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