A New Ceramide from the Florets of Carthamus tinctorius
- 39 Downloads
A new ceramide, rel-(3S,4S,5S)-3-[(2S)-2-hydroxyheneicosanoylamino]-4-hydroxy-5-[(4Z)-tetradecan-4-ene]-2,3,4,5-tetrahydrofuran (1), was isolated from the florets of Carthamus tinctorius along with two compounds, 10,12-nonacosanedione (2) and apigenin-7-O-β-apiofuranosyl-6,8-di-C-β-glucopyranoside (3), for the first time. Their structures were elucidated by means of spectral techniques including MS and 1D/2D NMR.
KeywordsCarthamus tinctorius ceramide
This work was supported by the National Natural Science Foundation of China (81274058), the Specialized Research Fund for the Doctoral Program of Higher Education of China (20113237110010), and the National Key Technology R&D Program (2008BAI51B01). This research was also financially supported by a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).
- 1.H. Z. Zheng, Z. H. Dong, and J. She, Modern Study of Traditional Chinese Medicine, Xue Yuan Press, Beijing, China, 1998.Google Scholar
- 5.H. Sato, H. Kawagishi, T. Nishimura, S. Yoneyama, Y. Yoshimoto, S. Sakamura, A. Furusaki, S. Katsuragi, and T. Serotobenine, Agric. Biol. Chem., 49, 2969 (1985).Google Scholar
- 7.H. T. Chang, H. X. Han, and P. F. Tu, Drugs Clin., 14, 201 (1999).Google Scholar
- 9.C. Qu, S. J. Yue, H. Lin, J. Kai, G. X. Shang, Y. P. Tang, W. W. Tao, and J. A. Duan, Chin. Trad. Herb. Drugs, 13, 1872 (2015).Google Scholar