Chemistry of Natural Compounds

, Volume 53, Issue 2, pp 295–298 | Cite as

Two New ent-Labdane Diterpenes from the Roots of Euphorbia yinshanica

  • Ben-Yin Zhang
  • Heng-Xia Yin
  • De-Jun Zhang

Two new ent-labdane diterpenes, ent-3α,16-dihydroxylabda-8(17),12(E),14-triene (1) and ent-14(S),15-dihydroxylabda-8(17)-12(E)-dien-18-oic acid (2), were isolated from the roots of Euphorbia yinshanica. Their structures were elucidated on the basis of spectroscopic methods including HR-ESI-MS and 1D and 2D NMR. The cytotoxic activities against five tumor cell lines was also evaluated, but there was no significant activity.


Euphorbiaceae Euphorbia yinshanica ent-labdane diterpenes cytotoxic activity 



This work was supported by the National Natural Science Foundation of China (NSFC, Grant No. 31500049) and Postdoctoral Science Foundation of China (2014M552077).


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.State Key Laboratory of Plateau Ecology and AgricultureQinghai UniversityXiningP. R. China
  2. 2.College of Eco-Environmental EngineeringQinghai UniversityXiningP. R. China

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