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Chemistry of Natural Compounds

, Volume 53, Issue 2, pp 273–275 | Cite as

A New Sesquiterpenoid from Acanthopanax senticosus

  • Zhi-Feng Li
  • Qi Wang
  • Gang Chen
  • Shi-Lin Yang
  • Yu-Lin Feng
  • Yue-Hu Pei
Article

From the aerial part of Acanthopanax senticosus, a new sesquiterpenoid, guai-6-en-4β,10α,15-triol (1), was isolated. Its structure was characterized by extensive spectral methods, including 1D, 2D NMR, and HR-ESI-MS. The cytotoxicity against HL-60 and HeLa of the new compound was tested.

Keywords

Acanthopanax senticosus sesquiterpenoid n-butanol extract 

Notes

Acknowledgment

This work was supported by the National Natural Science Foundation of China (No. 81560638) and the Science and Technology Project of Jiangxi Province Education Department (No. KJLD14060). The authors thank Yi Sha and Wen Li for the measurements of NMR spectra.

References

  1. 1.
    J. Y. Zhang, Z. K. Yan, H. R. Li, B. X. Wang, W. Z. Zhang, H. Q. Zhao, and Chang Bai Shan Zhi Wu Yao Zhi [M], Changchun, JiLin People′s Publishing Company, 1982, pp. 774–778.Google Scholar
  2. 2.
    C. J. Shao, R. K. Kasai, J. D. Xu, and O. Tanaka, Chem. Pharm. Bull., 37, 42 (1989).CrossRefGoogle Scholar
  3. 3.
    C. J. Shao, R. K. Kasai, J. D. Xu, and O. Tanaka, Chem. Pharm. Bull., 36, 601 (1988).CrossRefGoogle Scholar
  4. 4.
    D. Takeshi, N. Sansei, and N. Yoshihisa, Acta Pharm. Sin., 22, 1057 (2001).Google Scholar
  5. 5.
    S. Nishibe, H. Kinoshita, H. Tadeda, and G. Okano, Chem. Pharm. Bull., 38, 1763 (1990).CrossRefPubMedGoogle Scholar
  6. 6.
    X. C. Li, D. L. Barnes, and I. A. Khan, Planta Med., 67, 776 (2001).CrossRefPubMedGoogle Scholar
  7. 7.
    J. N. Fang, A. Proksh, and H. Wagner, Phytochemistry, 24, 2619 (1985).CrossRefGoogle Scholar
  8. 8.
    Z. F. Li, Z. H. Wu, G. Chen, Q. H. Zhang, and Y. H. Pei, J. Asian Nat. Prod. Res., 11, 716 (2009).CrossRefPubMedGoogle Scholar
  9. 9.
    Z. F. Li, N. Xu, B. M. Feng, Q. H. Zhang, and Y. H. Pei, J. Asian Nat. Prod. Res., 12, 51 (2010).CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Zhi-Feng Li
    • 1
  • Qi Wang
    • 1
  • Gang Chen
    • 2
  • Shi-Lin Yang
    • 1
  • Yu-Lin Feng
    • 1
  • Yue-Hu Pei
    • 2
  1. 1.National Pharmaceutical Engineering Centre for Solid Preparation in Chinese Herbal MedicineJiangxi University of Traditional Chinese MedicineNanchangP. R. China
  2. 2.School of Traditional Chinese Materia MedicaShenyang Pharmaceutical UniversityShenyangP. R. China

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