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Chemistry of Natural Compounds

, Volume 53, Issue 2, pp 269–272 | Cite as

Phlotuberosides I and II, New Iridoid Glycosides from Phlomoides tuberosa

  • D. N. Olennikov
  • N. K. Chirikova
Article

Two new iridoid glycosides were isolated from subterranean organs of Phlomoides tuberosa (L.) Moench (Lamiaceae) growing in eastern Siberia and were identified based on UV, MS, and NMR spectral data as 6′-O-β-D-glucopyranosyl lamalbide (phlotuberoside I, 1) and 6′-O-α-D-galactopyranosyl lamalbide (phlotuberoside II, 2) in addition to 16 known compounds. Compound 2 showed greater anti-inflammatory activity in the 12-O-tetradecanoylphorbol acetate-induced inflammation model.

Keywords

Phlomoides tuberosa Lamiaceae 6-O-β-D-glucopyranosyl lamalbide 6-O-α-D-galactopyranosyl lamalbide anti-inflammatory activity 

Notes

Acknowledgment

The work was supported financially by SB RAS Project No. VI.62.1.8.

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Institute of General and Experimental Biology, Siberian BranchRussian Academy of SciencesUlan-UdeRussia
  2. 2.M. I. Ammosov North-Eastern Federal UniversityYakutskRussia

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