Chemistry of Natural Compounds

, Volume 53, Issue 2, pp 241–247 | Cite as

Hemisynthesis and Spectroscopic Characterization of Three New Chalcone Derivatives from Dorstenia barteri

  • Bathelemy Ngameni
  • Ghislain Wabo Fotso
  • Pantaleon Ambassa
  • Justin Kamga
  • Arif Dastan
  • Bonaventure Tchaleu Ngadjui

The hemisynthesis of three new chalcones, namely kenzanol, kelianol A, and kelianol B, from Dorstenia barteri (Moraceae) is described here for the first time. The synthetic pathways employed in this work involved the pyrolysis and catalytic hydrogenation of readily available and starting materials, 4-hydroxylonchocarpin and isobavachalcone, two major constituents of the herbaceous plant D. barteri. The structural elucidation of all the compounds was done by mass spectrometry, IR, UV, 1D and 2D NMR analysis, and also by comparison with previous reports.


Dorstenia barteri Moraceae 4-hydroxylonchocarpin isobavachalcone synthesis 



BN and BTN are grateful to the Chemistry Department of the University of Botswana for providing research facilities. BN and AD are also thankful to the Department of Chemistry, Ataturk University, Turkey for important support with the experimental equipment.


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Bathelemy Ngameni
    • 1
  • Ghislain Wabo Fotso
    • 2
  • Pantaleon Ambassa
    • 2
  • Justin Kamga
    • 2
  • Arif Dastan
    • 3
  • Bonaventure Tchaleu Ngadjui
    • 2
  1. 1.Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Medicine and Biomedical SciencesUniversity of Yaounde IYaoundeCameroon
  2. 2.Department of Organic Chemistry, Faculty of ScienceUniversity of Yaounde IYaoundeCameroon
  3. 3.Department of Chemistry, Faculty of ScienceAtaturk UniversityErzurumTurkey

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