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Chemistry of Natural Compounds

, Volume 53, Issue 2, pp 227–230 | Cite as

New Fatty Acid From a Gorgonian-Derived Xylaria sp. Fungus

  • Da-Wei Sun
  • Fei Cao
  • Min Liu
  • Fei-Fei Guan
  • Chang-Yun Wang
Article

A new fatty acid, (2E,4E,6S)-6-hydroxydeca-2,4-dienoic acid (1), along with six known compounds (2–7), were isolated from the gorgonian-derived fungus Xylaria sp. C-2, collected from the South China Sea. The structure of 1 was elucidated by 1D, 2D NMR, and MS spectrometry. The absolute configuration of 1 was determined by using the modified Mosher’s method. All of the isolated compounds were evaluated for their cytotoxic and antibacterial activities.

Keywords

gorgonian-derived fungus Xylaria sp. C10 unsaturated hydroxy fatty acid absolute configuration 

Notes

Acknowledgment

We thank Dr. Chang-Lun Shao, School of Medicine and Pharmacy, Ocean University of China, for sample collection. This work was supported by the National Natural Science Foundation of China (Nos. 81172977; U1406402) and the Special Financial Fund of Innovative Development of Marine Economic Demonstration Project (No. GD2012-D01-001).

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Da-Wei Sun
    • 1
  • Fei Cao
    • 1
  • Min Liu
    • 1
  • Fei-Fei Guan
    • 1
  • Chang-Yun Wang
    • 1
  1. 1.Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and PharmacyOcean University of ChinaQingdaoP. R. China

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