Laminarans and fucoidans from two Russian Far-East (Desmarestia viridis and Dictyota dichotoma) and four Vietnam species (Dictyota divaricata, Padina boryana, Sargassum duplicatum, and S. feldmannii) of brown algae were isolated and studied. Water-soluble polysaccharides from D. divaricata, P. boryana, and S. feldmannii were mainly fucoidans; from D. viridis, D. dichotoma, and S. duplicatum, approximately equal amounts of laminarans and fucoidans. All studied laminarans had a main chain of 1,3-bonded glucose residues with branching on C-6 with various ratios of 1,3:1,6 bonds. Fucoidans from D. viridis and D. dichotoma were medium- and low-sulfated heterogeneous polysaccharides; from D. divaricata, P. boryana, S. duplicatum, and S. feldmannii, sulfated galactofucans containing traces of mannose, xylose, and glucose. Galactofucans from D. divaricata, P. boryana, S. duplicatum, and S. feldmannii were not cytotoxic and exhibited antitumor activity against DLD-1 human colon carcinoma cells.
Similar content being viewed by others
References
M. T. Ale, J. D. Mikkelsen, and A. S. Meyer, Mar. Drugs, 9, 2106 (2011).
A. I. Usov and M. I. Bilan, Usp. Khim., 78, 846 (2009).
T. N. Zvyagintseva, I. N. Shirokova, and L. A. Elyakova, Bioorg. Khim., 20, 1349 (1994).
Y. T. Kim, E. H. Kim, C. Cheong, D. L. Williams, C. W. Kim, and S. T. Lim, Carbohydr. Res., 328, 331 (2000).
M. M. Bradford, Anal. Biochem., 72, 248 (1976).
M. Rabanal, N. M. Ponce, D. A. Navarro, R. M. Gomez, and C. A. Stortz, Carbohydr. Polym., 101, 804 (2014).
M. M. D. Hussein, S. T. Fouad, and A. F. Abdel-Fattah, Carbohydr. Res., 72, 171 (1979).
A. F. Abdel-Fattah, M. M. D. Hussein, and S. T. Fouad, Phytochemistry, 17, 741 (1978).
T. M. Silva, L. G. Alves, K. C. De Queiroz, M. G. Santos, C. T. Marques, S. F. Chavante, H. A. Rocha, and E. L. Leite, Braz. J. Med. Biol. Res., 38, 523 (2005).
M. M. D. Hussein, A. Abdel-Aziz, and H. M. Salem, Phytochemistry, 19, 2133 (1980).
P. Karmakar, T. Ghosh, S. Sinha, S. Saha, P. Mandal, P. K. Ghosal, and B. Ray, Carbohydr. Polym., 78, 416 (2009).
N. V. S. A. V. P. Rao, K. V. Sastry, and E. V. Rao, Phytochemistry, 23, 2531 (1984).
H. D. Cuong, T. T. Thuy, T. T. Huong, B. M. Ly, and T. T. Van, Nat. Prod. Res., 29, 411 (2015).
S. Preeprame, K. Hayashi, J. B. Lee, U. Sankawa, and T. Hayashi, Chem. Pharm. Bull., 49, 484 (2001).
M. I. Bilan, A. A. Grachev, A. S. Shashkov, T. T. Thuy, T. T. Van, B. M. Ly, N. E. Nifantiev, and A. I. Usov, Carbohydr. Res., 377, 48 (2013).
P. Hu, R. Xue, Z. Li, M. Chen, Z. Sun, J. Jiang, and C. Huang, Carbohydr. Res., 390, 28 (2014).
W. Zhu, V. E. C. Ooi, P. K. S. Chan, and P. O. Ang, Jr., Biochem. Cell Biol., 81, 25 (2003).
M. Dubois, K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith, Anal. Chem., 28, 350 (1956).
V. L. Singleton and J. A. Rossi, Am. J. Enol. Vitic., 16, 144 (1965).
K. S. Dodgson and R. G. Price, Biochem. J., 84, 106 (1962).
Acknowledgment
The work was sponsored by RFBR Grants 16-33-60023 mol_a_dk and 16-54-540004 V′et-_a.
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2017, pp. 5–8.
Rights and permissions
About this article
Cite this article
Shevchenko, N.M., Usol′tseva (Men′shova), R.V., Ishina, I.A. et al. Structural Characteristics and in vitro Antitumor Activity of Water-Soluble Polysaccharides from Brown Algae of the Russian Far East and Vietnam. Chem Nat Compd 53, 1–5 (2017). https://doi.org/10.1007/s10600-017-1897-3
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10600-017-1897-3