Chemistry of Natural Compounds

, Volume 52, Issue 2, pp 352–355 | Cite as

Chemical Constituents of Thymus seravschanicus and Their Biological Activity

  • N. Z. Mamadalieva
  • E. Ovidi
  • V. Vinciguerra
  • M. L. Ashour
  • Sh. S. Azimova
  • A. Tiezzi

The genus Thymus includes 250 reported wild species, which makes it one of the most systematically complicated genera of the family Lamiaceae. Plants of the genus Thymus are perennial herbs and subshrubs that grow in Europe, North Africa, and Asia [1]. The Uzbekistan flora contains only the two species T. seravschanicus Klokov and T. incertus Klokov [2]. The former is a perennial plant that grows in Pamir-Alai and Tian Shan mountains (Central Asia) and is known as togjambil, which is widely used in Uzbek folk medicine as an antimicrobial and antiseptic agent for treating throat diseases, bronchitis, toothache, radiculitis, neuritis, and spasms [3, 4].

Nevertheless, the chemical composition and biological activity of T. seravschanicus have not yet been studied. We investigated the chemical composition and cytotoxic and antioxidant activity of extracts of the aerial part of T. seravschanicus.

Antiproliferative activity of the MeOH, CHCl 3, and H 2O extracts of aerial parts of T....


MeOH DPPH Gallic Acid Aerial Part Thymol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



One of us (NZM) thanks the UNESCO-L’OREAL foundation for sponsoring the research.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • N. Z. Mamadalieva
    • 1
  • E. Ovidi
    • 2
  • V. Vinciguerra
    • 2
  • M. L. Ashour
    • 3
  • Sh. S. Azimova
    • 1
  • A. Tiezzi
    • 2
  1. 1.S. Yu. Yunusov Institute of the Chemistry of Plant SubstancesAcademy of Sciences of the Republic of UzbekistanTashkentUzbekistan
  2. 2.Department for the Innovation in Biological, Agro-Food and Forestal SystemsTuscia UniversityViterboItaly
  3. 3.Department of Pharmacognosy, Faculty of PharmacyAin Shams UniversityAbbasiaEgypt

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