Chemistry of Natural Compounds

, Volume 52, Issue 1, pp 19–22 | Cite as

Antimicrobial Stilbenoids from Bletilla yunnanensis

  • Xinzhou Yang
  • Jing Yang
  • Chan Xu
  • Jingnan Lv
  • Chao Wang
  • Ping Song

A new bisphenanthrene, 2,2′,4,4′,7,7′-hexamethoxy-9,9′,10,10′-tetrahydro-1,1′-biphenanthrene (1), was isolated with five known phenanthrenes (2–6) from the tubers of Bletilla yunnanensis Schltr. Their structures were elucidated by detailed spectroscopic analyses. Compounds 4 and 5 exhibited potential antibacterial activity against two Gram positive strains, Staphylococcus aureus and S. epidermidis, with the MIC values of 6.25–25 μg/mL.


Bletilla yunnanensis stilbenoids phenanthrenes antimicrobial activity 



The work was financially supported by National Natural Science Foundation of China grants (No. 81102798), Natural Science Foundation of Qinghai Province (No. 2012-Z-904), Wuhan Youth Chenguang Program of Science and Technology (No. 2013070104010028), and Technology Foundation for Selected Overseas Chinese Scholar, Ministry of Personnel of China (No. BZY12006).


  1. 1.
    China National Corporation of Traditional and Herbal Medicine, The Handbook of Chinese Traditional Medicine Resources in China, Science Press, Beijing, 1994, p. 1519.Google Scholar
  2. 2.
    Editorial Board of China Herbal, State Administration of Traditional Chinese Medicine, China Herbal (7), Shanghai Scientific and Technical Publishers, Shanghai, 1999, p. 640.Google Scholar
  3. 3.
    L. Bai, T. Kato, K. Inoue, M. Yamaki, and S. Takagi, Phytochemistry, 33, 1481 (1993).CrossRefGoogle Scholar
  4. 4.
    M. Yamaki, L. Bai, K. Inoue, and S. Takagi, Phytochemistry, 28, 3503 (1989).CrossRefGoogle Scholar
  5. 5.
    S. Takagi, M. Yamaki, and K. Inoue, Phytochemistry, 22, 1011 (1983).CrossRefGoogle Scholar
  6. 6.
    X. Z. Yang, C. P. Tang, and Y. Ye, J. Asian Nat. Prod. Res., 8, 47 (2006).CrossRefPubMedGoogle Scholar
  7. 7.
    K. Kostecki, D. Engelmeier, T. Paucher, O. Hofer, S. Vajrodaya, and H. Greger, Phytochemistry, 65, 99 (2004).CrossRefPubMedGoogle Scholar
  8. 8.
    M. H. Yang, L. Cai, H. X. Fang, S. C. Yang, Y. S. Fang, and Z. T. Ding, Chem. Nat. Compd., 50, 88 (2014).CrossRefGoogle Scholar
  9. 9.
    L. G. Lin, X. Z. Yang, C. P. Tang, C. Q. Ke, J. B. Zhang, and Y. Yang, Phytochemistry, 69, 457 (2008).CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.College of PharmacySouth-Central University for NationalitiesWuhanP. R. China
  2. 2.Division of Science & TechnologyQinghai University for NationalitiesXilingP. R. China

Personalised recommendations