Antimicrobial Stilbenoids from Bletilla yunnanensis
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A new bisphenanthrene, 2,2′,4,4′,7,7′-hexamethoxy-9,9′,10,10′-tetrahydro-1,1′-biphenanthrene (1), was isolated with five known phenanthrenes (2–6) from the tubers of Bletilla yunnanensis Schltr. Their structures were elucidated by detailed spectroscopic analyses. Compounds 4 and 5 exhibited potential antibacterial activity against two Gram positive strains, Staphylococcus aureus and S. epidermidis, with the MIC values of 6.25–25 μg/mL.
KeywordsBletilla yunnanensis stilbenoids phenanthrenes antimicrobial activity
The work was financially supported by National Natural Science Foundation of China grants (No. 81102798), Natural Science Foundation of Qinghai Province (No. 2012-Z-904), Wuhan Youth Chenguang Program of Science and Technology (No. 2013070104010028), and Technology Foundation for Selected Overseas Chinese Scholar, Ministry of Personnel of China (No. BZY12006).
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