Diverse Terpenoids from the Leaves of Clerodendrum trichotomum
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Clerodendrum trichotomum Thunb., whose leaves and twigs are known in Chinese as “Chou-Wu-Tong” due to the unpleasant smell, belongs to the Verbenaceae family. Its roots, stems, leaves, flowers, and fruits have been used as medicine due to their antihypertensive, sedative, analgesic, and anti-inflammatory properties . Pharmacological studies on this plant have suggested that the diterpenoids exhibit distinct feeding stimulant activity to the adult turnip sawfly  and that these triterpenoids have potential as an antibacterial agent . In the course of our study on the systematic chemical constituents of the EtOH extract of the leaves of C. trichotomum, a series of steroids  and cyclohexylethanoids , together with diverse terpenoids (1–15), including monoterpenoids, sesquiterpenoids, diterpenoids, and triterpenoids, were isolated and elucidated by a comprehensive analysis of the spectral data, including NMR and ESI-MS, and comparison of their NMR data with those in the...
KeywordsCDCl3 EtOH Gansu Province Betulinic Acid Lupeol
This work was supported by the National Natural Science Foundation of China (Nos. 21375136 and 81303202).
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