Chemistry of Natural Compounds

, Volume 51, Issue 5, pp 840–843 | Cite as

Two New Flavones from Hypericum chinense and Their Anti-Tobacco Mosaic Virus Activity

  • Bin Zhou
  • Yinke Li
  • Xianxue Wu
  • Ming Li
  • Yanqing Ye
  • Xuemei Gao
  • Qiufen Hu

Two new flavones, 6,4′-dimethoxy-8-formylflavone (1) and 6,7-dimethoxy-8-acetyl-4′-hydroxyflavone (2), together with five known flavones (3–7), were isolated from the leaves and stems of Hypericum chinense. The structure of 1–7 was elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1, 2, 6, and 7 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 shows high anti-TMV activity with an inhibition rate of 31.4%, which is close to that of the positive control.


Hypericum chinense flavones anti-tobacco mosaic virus 



This research was supported by the National Natural Science Foundation of China (No. 21362044), the Excellent Scientific and Technological Team of Yunnan High School (2010CI08), and the Yunnan University of Nationalities Green Chemistry and Functional Materials Research for Provincial Innovation Team (2011HC008).


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Bin Zhou
    • 1
  • Yinke Li
    • 1
    • 2
  • Xianxue Wu
    • 2
  • Ming Li
    • 2
  • Yanqing Ye
    • 1
  • Xuemei Gao
    • 1
  • Qiufen Hu
    • 1
  1. 1.Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of EducationYunnan University of NationalitiesKunmingP. R. China
  2. 2.College of Resource and EnvironmentYuxi Normal UniversityYuxiP. R. China

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