Chemical Constituents and Antibacterial Activities of Compounds from Lentinus edodes
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The genus Lentinus (Lentinaceae, higher Basidiomycetes) consists of about 8 species, distributed mainly in Asia; many of these species are used as edible mushrooms in China. These edible mushrooms may have important salutary effects on health or even in treating disease. This is the case with the medicinal shiitake mushroom Lentinus edodes (Berk.) Singer . It has been shown in preclinical studies that extracts from L. edodes have antibiotic, antiviral, and antitumor activities . No systematically chemical constituent of this species has been reported hitherto. We have conducted a systematic phytochemical study on the whole plant of L. edodes and have isolated and identified six known compounds (1–6). All these compounds were tested for antibacterial activities against five bacteria. Within the series of compounds tested, compounds 1, 2, and 5 exhibited moderate activities against Escherichia coli, Bacillus cereus, Staphyloccocus aureus, Erwinia carotovora, and Bacillus subtilis...
KeywordsCDCl3 Antibacterial Activity EtOAc CD3OD Bacillus Cereus
This work was funded by the National Natural Science Foundation of China (No. 21172196).
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