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Chemistry of Natural Compounds

, Volume 51, Issue 3, pp 592–594 | Cite as

Chemical Constituents and Antibacterial Activities of Compounds from Lentinus edodes

  • Jia Chen
  • Shi-Lei Wei
  • Kun Gao
Article

The genus Lentinus (Lentinaceae, higher Basidiomycetes) consists of about 8 species, distributed mainly in Asia; many of these species are used as edible mushrooms in China. These edible mushrooms may have important salutary effects on health or even in treating disease. This is the case with the medicinal shiitake mushroom Lentinus edodes (Berk.) Singer [1]. It has been shown in preclinical studies that extracts from L. edodes have antibiotic, antiviral, and antitumor activities [1]. No systematically chemical constituent of this species has been reported hitherto. We have conducted a systematic phytochemical study on the whole plant of L. edodes and have isolated and identified six known compounds (16). All these compounds were tested for antibacterial activities against five bacteria. Within the series of compounds tested, compounds 1, 2, and 5 exhibited moderate activities against Escherichia coli, Bacillus cereus, Staphyloccocus aureus, Erwinia carotovora, and Bacillus subtilis...

Keywords

CDCl3 Antibacterial Activity EtOAc CD3OD Bacillus Cereus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This work was funded by the National Natural Science Foundation of China (No. 21172196).

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.School of Biotechnology and Chemical Engineering, Ningbo Institute of TechnologyZhejiang UniversityNingboPeople’s Republic of China
  2. 2.State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical EngineeringLanzhou UniversityLanzhouPeople’s Republic of China

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