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Chemistry of Natural Compounds

, Volume 50, Issue 3, pp 503–510 | Cite as

Synthesis of bis-Tetrahydroisoquinolines Based on Homoveratrylamine and a Series of Dibasic Acids. 3.

  • A. Sh.Saidov
  • E. Yu. Mazur
  • K. K. Turgunov
  • B. Tashkhodzhaev
  • M. G. Levkovich
  • V. I. Vinogradova
Article

Pyrido- and [1, 4]-oxazinoisoquinolines, bis-tetrahydroisoquinolines, the alkaloid corydaldine, cleavage products, and a series of intermediates were prepared from homoveratrylamine and dibasic acids (glutaric and diglycolic) using a Bischler–Napieralski reaction. Their structures were confirmed using IR and NMR spectra and an x-ray crystal structure analysis.

Keywords

glutaric and diglycolic acids homoveratrylamine amides Bischler–Napieralski reaction isoquinolines 

Notes

Acknowledgment

The work was financed by the Basic Research Program of KKRNT, RUz, Grant FA-F7-T185.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • A. Sh.Saidov
    • 1
  • E. Yu. Mazur
    • 2
  • K. K. Turgunov
    • 2
  • B. Tashkhodzhaev
    • 2
  • M. G. Levkovich
    • 2
  • V. I. Vinogradova
    • 2
  1. 1.A. Navoi Samarkand State UniversityTashkentUzbekistan
  2. 2.S. Yu. Yunusov Institute of the Chemistry of Plant SubstancesAcademy of Sciences of the Republic of UzbekistanTashkentUzbekistan

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