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A New Polyunsaturated Acid from the Marine-Derived Streptomyces violans (No. HTTA-F04129)

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Chemistry of Natural Compounds Aims and scope

An Erratum to this article was published on 01 January 2015

One new polyunsaturated acid (1), together with two known compounds, benzodipyran (2) and 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (3) were isolated from the fermentation broth of the marine Streptomyces violans (strain HTTA-F04129). Their structures were elucidated on the basis of 1D and 2D NMR, HR-FAB-MS spectra, and IR spectra. Bioassay results showed that compound 1 possessed significant selective antitumor activity against A2780 cell line in vitro with IC50 value 4.36 μM and antibacterial activity against E. coli with MIC value of 25 μg/mL.

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REFERENCES

  1. S. Dharmaraj, World J. Microbiol. Biotechnol., 26, 2123 (2010).

    Article  CAS  Google Scholar 

  2. P. Sun, K. N. Maloney, S. Nama, N. M. Haste, R. Raju, W. Aalbersberg, P. R. Jensen, V. Nizet, M. E. Hensler, and W. Fenical, Bioorg. Med. Chem., 19, 6557 (2011).

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  3. P. Fu, C. Yang, Y. Wang, P. Liu, Y. Ma, L. Xu, M. Su, K. Hong, and W. Zhu, Org. Lett., 14 (9), 2422 (2012).

    Article  CAS  PubMed  Google Scholar 

  4. G. K. Oleinikova, O. I. Ivchuk, V. A. Denisenko, E. L. Chaikina, N. I. Menzorova, O. I. Nedashkovskaya, and T. A. Kuznetsova, Chem. Nat. Compd., 42, 713 (2006).

    Article  CAS  Google Scholar 

  5. O. I. Zhuravleva, E. V. Leshchenko, Sh. Sh. Afiyatullov, M. P. Sobolevskaya, V. A. Denisenko, and L. S. Shevchenko, Chem. Nat. Compd., 47, 494 (2011).

    Article  CAS  Google Scholar 

  6. K. Eckardt, D. Tresselt, and W. Ihn, Tetrahedron, 34 (4), 399 (1978).

    Article  CAS  Google Scholar 

  7. Y. Kashiwada, G. I. Nonaka, and I. Nishioka, Chem. Pharm. Bull., 32, 3493 (1984).

    Article  CAS  Google Scholar 

  8. J. Xu, J. Kjer, J. Sendker, V. Wray, H. Guan, R. Edrada, W. Lin, J. Wu, and P. Proksch, J. Nat. Prod., 72, 665 (2009).

    Google Scholar 

  9. T. Mosmann, Immunol. Methods, 65, 55 (1983).

    Article  CAS  Google Scholar 

  10. N. Erdemoglu, S. Ozkan, and F. Tosun, Phytochem. Rev., 6, 197 (2007).

    Article  CAS  Google Scholar 

Download references

ACKNOWLEDGMENT

This work was supported by the Natural Science Foundation of China (21102020), the National High Technology Research and Development Program (863 Program) of China (2011AA10A202-2), and the National Technologies R&D Program (2011BAE06B04).

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Authors and Affiliations

  1. School of Chemical Engineering and Light Industry, Guangdong University of Technology, 510006, Guangzhou, People’s. Republic of China

    H. Huang, Y. Cao & K. Zhang

  2. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, 100191, Beijing, People’s. Republic of China

    H. Huang & W. Lin

  3. First Institute of Oceanography, State Oceanic Administration, 266061, Qingdao, People’s. Republic of China

    L. Tian

  4. Qingdao University of Science &Technology, Qingdao, 266042, People’s. Republic of China

    L. Tian

Authors
  1. H. Huang
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  2. Y. Cao
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  3. L. Tian
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  4. W. Lin
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  5. K. Zhang
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Corresponding author

Correspondence to W. Lin.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2014, pp. 349–351.

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Huang, H., Cao, Y., Tian, L. et al. A New Polyunsaturated Acid from the Marine-Derived Streptomyces violans (No. HTTA-F04129). Chem Nat Compd 50, 402–404 (2014). https://doi.org/10.1007/s10600-014-0970-4

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  • DOI: https://doi.org/10.1007/s10600-014-0970-4

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