Chemistry of Natural Compounds

, Volume 50, Issue 2, pp 357–359 | Cite as

Flavonoids and Antioxidant Activity of Thapsia garganica from Algeria

  • Salih Chibani
  • Muhammad Al-Dabbas
  • S. Abuhamdah
  • Talal Aburjai
  • Reguia Bencheraiet
  • Ahmed Kabouche
  • Maurice Jay
  • Zahia Kabouche

In continuation of our investigation of flavonol glycoside distribution in Algerian medicinal plants [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12], we report here our study on the aerial parts of Thapsia garganica L. (Apiaceae) [13]. This is the first time that flavonoids are isolated from this species from which the roots are traditionally used to treat rheumatism [14].

The aerial parts of Thapsia garganica L. (Apiaceae) were collected during the flowering period in May (2010) at Constantine, Algeria. A voucher specimen was deposited at the Herbarium of the Laboratory under the code number LOST.Tg.05.05.

Air dried aerial parts of Thapsia garganica (2000 g) were macerated three times with 70% MeOH solution. The hydroalcoholic solution was concentrated under reduced pressure to dryness, and the residue was dissolved in hot water (1000 mL) and kept in the cold overnight. After filtration, the aqueous solution was successively extracted with EtOAc once and with n-BuOH for three times; then the...


DPPH EtOAc Luteolin Apigenin Isorhamnetin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors thank the ANDRS and MESRS (DG/RSDT), Algeria for financial support.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Salih Chibani
    • 1
  • Muhammad Al-Dabbas
    • 2
  • S. Abuhamdah
    • 2
  • Talal Aburjai
    • 2
  • Reguia Bencheraiet
    • 1
  • Ahmed Kabouche
    • 1
  • Maurice Jay
    • 3
  • Zahia Kabouche
    • 1
  1. 1.University of Constantine 1, Department of Chemistry, Laboratory of Therapeutic Substances (LOST)ConstantineAlgeria
  2. 2.Department of Pharmaceutical Sciences, Faculty of PharmacyUniversity of JordanAmmanJordan
  3. 3.Universite Claude-Bernard, Laboratoire de PhytochimieLyonFrance

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