In order to investigate its bioactive compounds, we studied the chemical constituents of the seeds of Allium tuberosum systematically. Our detailed investigation of its seeds has led to the discovery of a new saponin. The new steroidal saponin, named tuberoside B, was isolated from the seeds of Allium tuberosum Rottl. ex Spreng. On the basis of acid hydrolysis, comprehensive spectroscopic analyses and comparison with spectral data of the new compound, its structure was established as (24S,25S)-5β-spirostan-2α,3β,5,24-tetraol 3-O-α-L-rhamnopyranoyl-(1 → 2)-O-[α-L-rhamnopyranosyl-(1 → 4)]-β-D-glucopyranoside. The new compound was identified by direct comparison with authentic samples (co-TLC, IR, MS, NMR) and with reported spectral and physical data. This paper deals with the isolation and structural elucidation of the new saponin.
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Acknowledgment
The work are supported by National Natural Science Foundation of China (31171747), the Fundamental Research Funds for the Central Universities and the National Special Fund for State Key Laboratory of Bioreactor Engineering, Grant No. 2060204.The authors are grateful for the assistance of Wang Xi, Center of Analysis & Research, East China University of Science and Technology, Shanghai, China, and Yu Yinghao, Center of Analysis & Research, Shanghai Normal University, Shanghai, P. R. China.
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2013, pp. 930–933.
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Hu, G., Lu, Y., Yu, W. et al. A Steroidal Saponin from the Seeds of Allium tuberosum . Chem Nat Compd 49, 1082–1086 (2014). https://doi.org/10.1007/s10600-014-0825-z
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DOI: https://doi.org/10.1007/s10600-014-0825-z