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Chemistry of Natural Compounds

, Volume 49, Issue 4, pp 632–634 | Cite as

11-Hydroxyisocom-2-en-5-one, a new sesquiterpenoid from Echinops spinosissimus

  • Zhi-Yu Ni
  • Yuta Nagashima
  • Man-Li Zhang
  • Yu-Fang Wang
  • Mei Dong
  • Francoise Sauriol
  • Chang-Hong Huo
  • Qing-Wen Shi
  • Yu-Cheng Gu
  • Hiromasa Kiyota
Article
  • 121 Downloads

A novel isocomene sesquiterpenoid, 11-hydroxyisocom-2-en-5-one, was isolated from the roots of Echinops spinosissimus subsp. spinosus Greuter. The structure was characterized on the basis of NMR spectroscopic methods, including 1H–1H COSY, HMBC, HSQC, and NOESY experiments.

Keywords

NMR 113Echinops spinosissimus subsp. spinosus Greuter roots isocomenes sesquiterpenoids structure elucidation 

Notes

Acknowledgment

The authors gratefully acknowledge financial support from the National Natural Science Foundation of China (81072551 and 81241101), the Key Projects of Science & Technology of Hebei Province (11276103D-89), and the Scientific Research Foundation of Hebei Province (08B032 and C2010000489). We also wish to extend our sincere thanks for financial support from Syngenta Ltd. (2011-Hebei Medical University-Syngenta-03) and JSPS KAKENHI (Grant Numbers 19580120, 22560112, and 25450144).

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Zhi-Yu Ni
    • 1
  • Yuta Nagashima
    • 2
  • Man-Li Zhang
    • 3
  • Yu-Fang Wang
    • 3
  • Mei Dong
    • 1
  • Francoise Sauriol
    • 4
  • Chang-Hong Huo
    • 3
  • Qing-Wen Shi
    • 1
    • 3
  • Yu-Cheng Gu
    • 5
  • Hiromasa Kiyota
    • 2
  1. 1.Department of Forensic MedicineHebei Medical University, Hebei Key Laboratory of Forensic MedicineShijiazhuangP. R. China
  2. 2.Graduate School of Agricultural ScienceTohoku UniversityAoba-kuJapan
  3. 3.School of Pharmaceutical Sciences & College of Basic MedicineHebei Medical UniversityShijiazhuangP. R. China
  4. 4.Department of ChemistryQueen’s UniversityKingstonCanada
  5. 5.Syngenta Jealott’s Hill International Research CentreBracknellUK

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