Flavonoids from Trachelospermum jasminoides
The stems and leaves of Trachelospermum jasminoides (Apocynaceae) are a traditional Chinese medicine named “Luoshiteng” and are used for the treatment of rheumatism, pharyngitis, sciatica, swelling of throat, viper bite, and wounds . Modern pharmacological research shows that T. jasminoides has antibacterial, antitumor, anti-inflammatory, antalgic, antiviral, and immunoregulating activities [2, 3, 4, 5]. Previous phytochemical studies led to the isolation of flavonoids, lignans, terpenoids, steroids, and alkaloids from this plant [6, 7, 8, 9]. In the search for its biologically active constituents, 15 flavonoids were isolated from this plant and 3–9 of them were firstly reported from the genus Trachelospermum.
The stems and leaves of T. jasminoides were purchased in Nanjing, Jiangsu Province, People’s Republic of China, in March, 2009 and were authenticated by Prof. Mian Zhang, Research Department of Phamacognosy, China Pharmaceutical University. The stems and leaves of T....
KeywordsFlavonoid Quercetin Rutin EtOAc Kaempferol
This work was supported by the Natural Science Foundation of Jiangsu Province, China (Grant No. BK2010594). We are grateful to Prof. Wen-Bin Shen (Center of Instrumental Analysis, China Pharmaceutical University) for measuring NMR data.
- 1.The People’s Republic of China Pharmacopoeia Committee, Chinese Pharmacopeia, 1st part, 2005, p. 190.Google Scholar
- 6.Sakushima, Nature Med., 56, 159 (2002).Google Scholar
- 8.X. Q. Tan, H. S. Chen, M. Zhou, and Y. Zhang, Chin. Trad. Herb. Drugs, 37, 171 (2006).Google Scholar
- 10.J. X. Pu, J. F. Zhao, X. D. Yang, C. H. Li, and L. Li, Chin. Trad. Herb. Drugs, 36, 819 (2005).Google Scholar
- 11.Y. J. Wang, X. W. Yang, and Q. S. Guo, China J. Chin. Mater. Med., 33, 526 (2008).Google Scholar
- 12.Z. N. Wang, Z. Han, H. B. Cui, and H. F. Dai, J. Trop. Subtrop. Bot., 15, 359 (2007).Google Scholar
- 13.J. S. Li, B. Wang, Y. Y. Zhao, X. L. Li, and L. B. Ma, Acta Pharm. Sin., 31, 849 (1996).Google Scholar
- 14.G. M. Zhang, X. Y. Xu, and J. F. Xi, Chin. Trad. Patent Med., 30, 771 (2008).Google Scholar
- 15.D. W. Ou Yang, P. M. Yang, and D. Y. Kong, Chin. J. Pharm., 39, 898 (2008).Google Scholar