Compositional heterogeneity of sulfated polysaccharides synthesized by the brown alga Costaria costata
- 78 Downloads
Brown algae contain sulfated polysaccharides, fucoidans, that exhibit various biological activities . The variety of activities exhibited by fucoidans is related to their structural variations. It was shown that species of a single family (genus) of brown algae can contain sulfated polysaccharides that differ in structure and biological activity . Correspondingly, several different fractions of fucoidans can be isolated from a single species [3,4]. Our goal was to determine the composition of sulfated polysaccharides synthesized by the brown alga Costaria costata [Turn.] Saund (Laminariaceae), which is broadly distributed in seas of the Russian Far East.
Polysaccharides were isolated by acid extraction at room temperature  from specimens of C. costata collected in July in Troits Bay (Sea of Japan). The polysaccharide fraction was separated into fucoidan (F) and laminaran by chromatography over the hydrophobic sorbent Polikhrom-1 . The monosaccharide composition of the...
KeywordsMonosaccharide Brown Alga Fucose Uronic Acid Sulfated Polysaccharide
The work was supported by the RAS Presidium Basic Research Program “Molecular and Cellular Biology”.
- 1.A. I. Usov and M. I. Bilan, Usp. Khim., 78, No. 8, 846 (2009).Google Scholar
- 2.A. Cumashi, N. A. Ushakova, M. E. Preobrazhenskaya, A. D’Incecco, A. Piccoli, L. Totani, N. Tinari, G. E. Morozevich, A. E. Berman, M. I. Bilan, A. I. Usov, N. E. Ustyuzhanina, A. A. Grachev, C. J. Sanderson, M. Kelly, G. A. Rabinovich, S. Iacobelli, and N. E. Nifantiev, Glycobiology, 17, 541 (2007).PubMedCrossRefGoogle Scholar
- 5.T. I. Imbs, N. M. Shevchenko, S. V. Sukhoverkhov, T. L. Semenova, A. V. Skriptsova, and T. N. Zvyagintseva, Khim. Prir. Soedin., 661 (2009).Google Scholar