Chemistry of Natural Compounds

, Volume 47, Issue 5, pp 856–857 | Cite as

Alkaloids from the plant Haplophyllum griffithianum

  • D. R. Kodirova
  • Kh. A. Rasulova
  • N. D. Abdullaev
  • Kh. M. Bobakulov

Alkaloids from plants of the genus Haplophyllum (Rutaceae) exert a calming action on the central nervous system and have low toxicity [1]. Several of the alkaloids exhibit analgesic, anticonvulsive, soporific, sedative [2, 3], and estrogenic [4, 5] in addition to anticancer activity [6].

Furthermore, alkaloids of this genus are used in folk medicine to treat animals for helminths, diseases of the gastrointestinal tract, and respiratory organs of animals and humans. Rational use of pastures with incorporation of Haplophyllum species can facilitate the revitalization of animals and increase the production of the herd [7]. This all indicates that studies of plants of the genus Haplophyllum are promising.

H. griffithianum Boiss. is a perennial herbaceous plant indigenous to mountainous regions of Central Asia (southwest Pamir-Alai) and Afghanistan [8].

We studied for the first time the alkaloid composition of the previously unstudied plant H. griffithianumcollected during flowering in...


CDCl3 Alkaloid EtOH Aerial Part HMDS 
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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • D. R. Kodirova
    • 1
  • Kh. A. Rasulova
    • 1
  • N. D. Abdullaev
    • 1
  • Kh. M. Bobakulov
    • 1
  1. 1.S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences, Republic of UzbekistanTashkentUzbekistan

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