A new cyclic peptide from the marine fungal strain Aspergillus sp. AF119
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A new cyclic heptapeptide containing γ-aminobutyric acid in the ring, namely unguisin E (1), was isolated from the fermentation culture of Aspergillus sp. AF119. The structure was elucidated by spectroscopic analyses, including 1D and 2D NMR experiments, and HR ESI-Q-TOF mass spectrometry, and by comparison with those reported. Compound 1 was evaluated for its antimicrobial activities by the paper diffusion method.
Keywordsheptapeptide unguisin E Aspergillus sp. AF119
This work was financially supported by the Key Grant of the Chinese Ministry of Education (306010) and the 973 Program (2010CB833802).