Chemistry of Natural Compounds

, 47:669 | Cite as

Alkaloid content in various parts of Sophora flavescens

  • D. V. Sandanov
  • N. A. Pankrushina

Quinolizidine alkaloids are rather frequently encountered in plants of the family Fabaceae [1]. According to modern research, this alkaloid group is a chemotaxonomic marker for the genus Sophora L. [2]. We studied Sophora flavescens Soland., a medicinal plant that is widely used in traditional Eastern medicine [3, 4, 5]. A large number of recent publications concerns the isolation, identification, and pharmacological properties of alkaloids from roots of this plant [6, 7, 8]. However, the alkaloid content in other parts of the plant is insufficiently studied. Therefore, our goal was to study the accumulation dynamics of alkaloids in various parts of S. flavescens.

Raw material for analysis was collected in Chita Oblast in 2001–2002. Total alkaloids were obtained by the standard method [9]. The alkaloids were isolated and identified using HPLC, GC, and GC–MS.

According to the total alkaloids in the various parts of S. flavescens, the greatest amount of alkaloids was localized in the...


Alkaloid Total Alkaloid Alkaloid Content Matrine Accumulation Dynamic 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    A. S. Sadykov, Kh. A. Aslanov, and Yu. K. Kushmuradov, Quinolizidine Alkaloids (Chemistry, Stereochemistry, Biogenesis) [in Russian], Nauka, Moscow, 1975.Google Scholar
  2. 2.
    M. Iinuma and T. Tanaka, in: Proceedings of the 15 th International Botanical Congress, Yokohama, 1993, p. 399.Google Scholar
  3. 3.
    I. V. Sakaeva, E. I. Sakanyan, E. E. Lesnovskaya, and K. F. Blinova, Rastit. Resur., 37, 111 (2001).Google Scholar
  4. 4.
    G. B. Song, Q. Luo, J. Qin, L. Wang, Y. S. Shi, and C. X. Sun, Colloids Surf., B, 48, 1 (2006).CrossRefGoogle Scholar
  5. 5.
    T. M. Ehrman, D. J. Barlow, and P. J. Hylands, J. Chem. Inf. Model., 47, 2316 (2007).PubMedCrossRefGoogle Scholar
  6. 6.
    K. L. Miao, J. Z. Zhang, Y. Dong, and Y. F. Xi, Tianran Chanwu Yanjiu Yu Kaifa, 13, No. 2, 69 (2001).Google Scholar
  7. 7.
    J. P. Michael, Nat. Prod. Rep., 20, 458 (2003).PubMedCrossRefGoogle Scholar
  8. 8.
    C. Xi, Y. Changqing, Y. Xiaoqing, and W. Xiaoru, J. Chromatogr., B: Anal. Technol. Biomed. Life Sci., 812, No. 1–2, 149 (2004).Google Scholar
  9. 9.
    S. Okuda, I. Murakoshi, H. Kamata, Y. Kashida, J. Haginiwa, and K. Tsuda, Chem. Pharm. Bull., 13, No. 4, 482 (1965).PubMedGoogle Scholar
  10. 10.
    S. Yu. Yunusov, Alkaloids [in Russian], Fan, Tashkent, 1981.Google Scholar
  11. 11.
    D. V. Sandanov, Sib. Ekol. Zh., 6, 891 (2009).Google Scholar
  12. 12.
    H. Kondo, E. Ochiai, and K. Tsuda, Arch. Pharm., 275, 493 (1937).CrossRefGoogle Scholar
  13. 13.
    H. Kondo, Arch. Pharm., 226, 1 (1928).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  1. 1.Institute of General and Experimental Biology, Siberian Branch, Russian Academy of SciencesUlan-UdeRussia
  2. 2.Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of SciencesNovosibirskRussia
  3. 3.Novosibirsk State UniversityNovosibirskRussia

Personalised recommendations