A series of novel luteolin derivatives was synthesized employing the Vilsmeier-Haak-Arnold reaction from the intermediate compound 3′,4′,7-trichloro-5-hydroxyflavone, which was obtained from luteolin. These derivatives may be used to improve the pharmacological activities of luteolin.
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This work was supported by the Natural Science Foundation of Zhejiang Province (Y205706).
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Published in Khimiya Prirodnykh Soedinenii, No. 5, pp. 606–607, September–October, 2010.
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Li, J.F., Wang, L.S., Bai, H.Q. et al. Synthesis and structure characterization of novel luteolin derivatives . Chem Nat Compd 46, 716–718 (2010). https://doi.org/10.1007/s10600-010-9723-1
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DOI: https://doi.org/10.1007/s10600-010-9723-1