Chemistry of Natural Compounds

, Volume 46, Issue 4, pp 636–637 | Cite as

Flavonoids from Anemone tomentosa roots

  • H. B. Hu
  • X. D. Zheng
  • Y. F. Jian
  • H. S. Hu
  • Y. Li
  • Y. Q. Zhang

The genus Anemone (Ranunculaceae) comprises about 150 species, of which 52 are distributed in northern China. As triterpenoid saponins are the main effective components of the genus Anemone, it has extensive biological activities, such as antitumor, antibacterial, and insect antifeeding properties. Anemone tomentosa (Maxim.) Pei is a perennial herb that is commonly called “Da Huo Cao” in China [1]. Its roots have been used as traditional Chinese medicine for the treatment of dysentery, malaria, infantile malnutrition, carbuncles, etc. [2]. Previous phytochemical studies of A. tomentosa have led to the isolation of coumarins [3], triterpenoids, and sterols [4, 5], but there are no records of the flavonoid constituents. Herein we communicate the additional isolation and structural elucidation of eight known flavonoids 1–8, of which 1, 4, and 6 were isolated from plants of the genus Anemone for the first time. Flavonoids were found first in A. tomentosa.

Roots of A. tomentosawere...


MeOH Flavonoid EtOAc CD3OD Yellow Crystal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors are grateful to Prof. Xiaoqiang Guo for identifying the plant sample. The work was supported financially by the Science Research Project of Longdong University (XYZK0709).


  1. 1.
    Flora Reipublicae Popularis Sinicae, Chinese Flora, Science Press, Beijing, 1980, Vol. 28, 29 pp.Google Scholar
  2. 2.
    Northwest Institute of Botany, Flora of Qinling, Chinese Academy of Sciences, Science Press, Beijing, 1974, 278 pp.Google Scholar
  3. 3.
    H. R. Wang, S. L. Peng, M. K. Wang, J. T. Feng, and L. S. Ding, Acta Bot. Sin., 41, 107 (1999).Google Scholar
  4. 4.
    J. R. Wang, J. Q. Ma, S. L. Peng, J. T. Feng, and L. S. Ding, Acta Bot. Boreal. Occident. Sin., 18, 643 (1998).Google Scholar
  5. 5.
    X. Liao, S. L. Peng, B. G. Li, Y. Z. Chen, and L. S. Ding, Chin. Chem. Lett., 10, 1035 (1999).Google Scholar
  6. 6.
    M.-H. Yang and L.-Y. Kong, Chem. Nat. Comp., 44, 98 (2008).CrossRefGoogle Scholar
  7. 7.
    R. M. Yu, X. Li, H. J. Zhang, L. J. Wu, T. R. Zhu, W. Li, L. Y. Liu, and G. Zhang, Acta Bot. Sin., 34, 369 (1992).Google Scholar
  8. 8.
    K. R. Markham, B. Ternal, R. Stanley, H. Geiger, and T. J. Mabry, Tetrahedron, 34, 1389 (1978).CrossRefGoogle Scholar
  9. 9.
    Y. J. Lee and T. D. Wu, J. Chin. Chem. Soc., 48, 201 (2001).Google Scholar
  10. 10.
    K. D. Yoon, C. Y. Kim, and H. Huh, Korean J. Pharmacogn., 31, 224 (2000).Google Scholar
  11. 11.
    Y. Hirai, S. Sanada, Y. Ida, and J. Shoji, Chem. Pharm. Bull., 34, 82 (1986).Google Scholar
  12. 12.
    Z. J. Jia, G. J. Zhu, and W. H. Wang, J. Lanzhou Univ. (Nat. Sci. Edition), 27, 102 (1991).Google Scholar
  13. 13.
    K. R. Markham, R. W. Hammett, and D. J. Ofman, Phytochemistry, 31, 549 (1992).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • H. B. Hu
    • 1
  • X. D. Zheng
    • 1
  • Y. F. Jian
    • 2
  • H. S. Hu
    • 1
  • Y. Li
    • 1
  • Y. Q. Zhang
    • 1
  1. 1.College of Chemistry and Chemical EngineeringLongdong UniversityQingyangP. R. China
  2. 2.Science and Technology College of Agriculture and ForestryLongdong UniversityQingyangP. R. China

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