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Chemistry of Natural Compounds

, Volume 46, Issue 4, pp 621–622 | Cite as

Neutral lipids and biological activity of the CHCl3 extract of the aerial part of Silene guntensis

  • N. Z. Mamadalieva
  • N. T. Ul’chenko
  • N. K. Yuldasheva
  • A. A. Zhanibekov
  • D. R. Egamberdieva
  • A. I. Glushenkova
Article

Investigations of the plants from the genus Silene showed that they are sources of ecdysteroids [1] and that many of them contain significant quantities of biologically active compounds.

We studied lipids occurring in the CHCl3 extract of S. guntensis B. Fedtsch. during extraction from it of ecdysteroids in order to utilize the plant more completely and safely and to establish the effect of the lipid components on the effectiveness of the antibacterial and cytotoxic activity.

Neutral lipids were isolated by separating the extract over a column of silica gel into hydrocarbons (3.34%), esters of fatty acids (FAE) and alcohols (7.83), triacylglycerides (TAG) (2.48), free fatty acids (FFA) (3.12), aliphatic and polyprene alcohols (5.0), and compounds eluted by Et2O (19.58), CHCl3 (3.38), and MeOH (55.26).

It can be seen that FAE, FFA, and TAG made up 13.43% of the total.

Fatty acids were analyzed as the methyl esters using GLC (Table  1) [ 2].
Table 1

Fatty-Acid Composition of...

Keywords

Free Fatty Acid Antibacterial Activity HeLa Cell Cytotoxic Activity Neutral Lipid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Z. Saatov, M. B. Gorovits, and N. K. Abubakirov, Chem. Nat. Comp., 29, 551 (1993).CrossRefGoogle Scholar
  2. 2.
    N. T.Ul’chenko and A. I. Glushenkova, Khim. Prir. Soedin., 103 (2000).Google Scholar
  3. 3.
    T. Mosmann, J. Immunol. Methods, 65, 1–2, 55 (1983).CrossRefPubMedGoogle Scholar
  4. 4.
    J. Kim, M. R. Marshall, and C. Wie, J. Agric. Food Chem., 43, 2839 (1995).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • N. Z. Mamadalieva
    • 1
  • N. T. Ul’chenko
    • 1
  • N. K. Yuldasheva
    • 1
  • A. A. Zhanibekov
    • 1
  • D. R. Egamberdieva
    • 2
  • A. I. Glushenkova
    • 1
  1. 1.S. Yu. Yunusov Institute of the Chemistry of Plant SubstancesAcademy of Sciences of the Republic of UzbekistanTashkentUzbekistan
  2. 2.National University of UzbekistanTashkentUzbekistan

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