Chemistry of Natural Compounds

, Volume 46, Issue 3, pp 340–342 | Cite as

A new dihydroisocoumarin with an isoprenyl group from the endophytic fungus Cephalosporium sp.


A new dihydroisocoumarin derivative containing an isoprenyl group, 5-(3'-methylbut-2'-enyloxy)-3,4-dihydro8-hydroxy-3-methylisochromen-1-one (1), was isolated from the mangrove fungus Cephalosporium sp. from the South China Sea. The structure of compound 1 was established by comprehensive analysis of the spectral data, especially 2D NMR spectra.


dihydroisocoumarin endophytic fungus structure elucidation 



This work was supported by the National Natural Science Foundation of China (Nos. 40976077; 30901879; 40776073), the Research Fund for the Doctoral Program of Higher Education, Ministry of Education of China (No. 20090132110002), the Basic Research Program of Science and Technology, Ministry of Science and Technology of China (No. 2007FY210500), and the Open Research Fund Program of Key Laboratory of Marine Drugs (Ocean University of China), the Ministry of Education (No. KLMD (OUC) 200801).


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Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  1. 1.School of PharmacyGuangdong Medical CollegeDongguanP. R. China
  2. 2.School of Medicine and PharmacyOcean University of ChinaQingdaoP. R. China
  3. 3.School of Chemistry and Chemical EngineeringSun Yat-sen UniversityGuangzhouP. R. China

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