Rare natural products from the wood of Magnolia grandiflora
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Magnolia grandiflora L. (Magnoliaceae) is used in traditional Chinese medicine for the treatment of colds, headaches, and stomachache [1???]. The plant has also been used for the treatment of fever, diarrhea, rheumatism and arthritis . Various class of compounds such as sesquiterpenoids [3–5???], coumarins , phenylpropanoids , lignans , glycosides [7, 8???], alkaloids , and other compounds  have been reported from this plant. The present study describes the isolation and structure determination of seven compounds 1–7 from the wood of M. grandiflora.
Shade air-dried and powdered wood of M. grandiflora (22.0 kg) was extracted with 95% ethanol. The EtOH extract was concentrated under vacuum until EtOH was completely removed. The dried EtOH extract (170.17 g) was dissolved in distilled water and successively partitioned with n-hexane, dichloromethane, ethyl acetate, and n-butanol saturated with water. The dichloromethane-soluble fraction (27.40 g) was chromatographed on...