Skip to main content
SpringerLink
Log in

A new ten-membered lactone from Tubercularia sp. TF5, an endophytic fungus of Taxus mairei

  • Published:
Chemistry of Natural Compounds Aims and scope

One new ten-membered lactone (1) named (Z)-4,6,9-trihydroxy-10-nonyl-3,4,5,6,9,10-hexahydrooxecin-2-one along with 5-methoxycarbonylmellein (2) and cytochalasin D (3) were isolated from the culture of the endophytic fungus strain Tubercularia sp. TF5, originally separated from the inner bark of Taxus mairei obtained in Fujian Province, Southeast China. The structures of compounds 1–3 were elucidated by spectroscopic methods. The antimicrobial and cytotoxic activities of 1 were analyzed but it showed no significant activities.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. J. F. Wang, G. L. Li, Z. H. Zheng, Y. J. Huang, and W. J. Su, FEMS Microbiol. Lett., 193, 249 (2000).

    Article  CAS  PubMed  Google Scholar 

  2. Y. Y. Li, C. Lu, Z. Hu, Y. Huang, and Y. Shen, Nat. Prod. Res., 23, 70 (2008).

    Article  CAS  Google Scholar 

  3. J. R. Anderson, R. L. Edwards, and A. J. S. Whalley, J. Chem. Soc. Perkin Trans. I, 2185 (1983).

  4. J. F. Wang, Y. J. Zhang, W. J. Su, Y. Lu, Y. F. Zhao, and S. W. Ng, Acta Crystallogr., E59, 1233 (2003).

    Google Scholar 

  5. M. Eric and J. T. Eric, J. Chem. Soc. Perkin Trans. I, 3269 (1999).

  6. F. Mosmann, J. Immunol. Methods, 65, 55 (1983).

    Article  CAS  PubMed  Google Scholar 

  7. F. Hadacek and H. Greger, Phytochem. Anal., 11, 137 (2000).

    Article  CAS  Google Scholar 

Download references

Acknowledgment

This work was financially supported by the Science and Technology Project of Xiamen (3502Z20063017) and the Key Grant of Chinese Ministry of Education (No. 306010).

Author information

Authors and Affiliations

  1. Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, Xiamen Engineering Research Center of Marine Microbial Drug Discovery, Fujian Laboratory of Pharmaceutical Engineering, School of Life Science, Xiamen University, No. 422 South Siming Road, Xiamen, Fujiang, 361005, China

    Ren Xu, Chunhua Lu, Xuan Wu, Cheng Lin & Zhonghui Zheng

Authors
  1. Ren Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chunhua Lu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Xuan Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Cheng Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Zhonghui Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Zhonghui Zheng.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 6, pp. 670–671, November–December, 2009.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Xu, R., Lu, C., Wu, X. et al. A new ten-membered lactone from Tubercularia sp. TF5, an endophytic fungus of Taxus mairei . Chem Nat Compd 45, 797–799 (2009). https://doi.org/10.1007/s10600-010-9505-9

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10600-010-9505-9

Key words

Search

Navigation