Phytochemical study of Convolvulus subhirsutus growing in Uzbekistan

  • A. M. Gapparov
  • S. F. Aripova
  • A. D. Vdovin
  • V. U. Khuzhaev

Eight alkaloid derivatives of tropane, among which the major ones were convolvine and convolamine; the minor ones, phyllalbin, convolidine, nortropine, phyllalbin N-oxide, convolvidine, and conpropine, have been isolated previously from the aerial part of Convolvulus subhirsutus growing in Uzbekistan [1, 2]. Quantitative analysis found 0.6% total bases in the aerial part; 1.6%, in the roots. The contents of the major alkaloids convolvine and convolamine were 45-50% of the total mixture. In continuation of research on alkaloids of this plant collected near Tepar, Tashkent Oblast′, a base (15 mg) with mp 144–145°C that was identified as the known alkaloid convolicine was isolated by chromatography over a column of Al2O3 from the non-phenol part of total alkaloids after removal of convolvine and convolamine [3]. The benzene eluates contained an alkaloid (10 mg) with mp 178–179°C that was identified as confolidine.

The extract was neutralized to pH 7 after removal of the alkaloids, diluted...


Alkaloid Coumarin EtOAc Caffeic Acid Acid Ethyl Ester 
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  1. 1.
    A. M. Gapparov, N. A. Razzakov, and S. F. Aripova, Khim. Prir. Soedin., 242 (2007).Google Scholar
  2. 2.
    A. M. Gapparov, S. F. Aripova, N. A. Razzakov, and V. U. Khuzhaev, Khim. Prir. Soedin., 601 (2008).Google Scholar
  3. 3.
    N. A. Razzakov and S. F. Aripova, Khim. Prir. Soedin., 46 (2004).Google Scholar
  4. 4.
    W. A. Andreae, Can. J. Res., Sect. C. 26, 31 (1948).Google Scholar
  5. 5.
    G. V. Bukreeva and G. V. Pigulevskii, Zh. Prikl. Khim., 39, 7, 1541 (1966).Google Scholar
  6. 6.
    G. V. Pigulevskii and G. A. Kuznetsova, Zh. Obshch. Khim., 24, 12, 2174 (1954).Google Scholar
  7. 7.
    M. E. Perel′son, Yu. N. Sheinker, and G. P. Syrova, Khim. Prir. Soedin., 6 (1970).Google Scholar
  8. 8.
    N. F. Komissarenko, I. G. Levashova, and U. A. Akhmedov, Khim. Prir. Soedin., 247 (1984).Google Scholar
  9. 9.
    A. D. Vdovin, D. Batsuren, E. Kh. Batirov, M. R. Yagudaev, and V. M. Malikov, Khim. Prir. Soedin., 441 (1983).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • A. M. Gapparov
    • 1
  • S. F. Aripova
    • 1
  • A. D. Vdovin
    • 1
  • V. U. Khuzhaev
    • 1
  1. 1.S. Yu. Yunusov Institute of the Chemistry of Plant SubstancesAcademy of Sciences of the Republic of UzbekistanTashkentUzbekistan

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