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Chemistry of Natural Compounds

, Volume 45, Issue 3, pp 338–345 | Cite as

Plant coumarins. 4.* Synthesis of N-containing derivatives of oreoselone

  • A. V. Lipeeva
  • E. E. Shul’ts
  • M. M. Shakirov
  • G. A. Tolstikov
Article

Bromination of peucedanin by various reagents was studied. Conditions for forming 2-(1,3-dibromopropan-2-ylidene)-2H-furo[3,2-g][1]benzopyran-3,7-dione were found. Several 2-aminofuranocoumarins were synthesized by reaction of 2-bromoreoselone with derivatives of pyrrolidine, piperidine, and piperazine. The new compounds were interesting as potential biologically active compounds.

Key words

furanocoumarins bromoreoselone 2-(1-methylethylidene)-7H-furo[3,2-g][1]benzopyran-3,7-dione 

Notes

Acknowledgment

The work was supported financially by the Russian Foundation for Basic Research (Project No. 08-03-90200-Mong_a).

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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • A. V. Lipeeva
    • 1
  • E. E. Shul’ts
    • 1
  • M. M. Shakirov
    • 1
  • G. A. Tolstikov
    • 1
  1. 1.N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian BranchRussian Academy of SciencesNovosibirskRussia

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