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Chemistry of Natural Compounds

, Volume 44, Issue 5, pp 606–611 | Cite as

Synthesis of lupane and 19β,28-epoxy-18α-oleanane 2,3-seco-derivatives based on betulin

  • I. A. Tolmacheva
  • A. V. Nazarov
  • O. A. Maiorova
  • V. V. Grishko
Article

The α-hydroxyoximes of methyl betulonate and allobetulone were synthesized. Beckmann fragmentation of them produced the lupane and 19β,28-epoxy-18α-oleanane 2,3-seco-derivatives.

Key words

2,3-seco-triterpenoids betulin allobetulin Beckmann fragmentation 

Notes

Acknowledgment

The work was supported financially by the RFBR Grant No. 08-03-00265a.

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Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  • I. A. Tolmacheva
    • 1
  • A. V. Nazarov
    • 1
  • O. A. Maiorova
    • 1
  • V. V. Grishko
    • 1
  1. 1.Institute of Chemical Engineering, Ural BranchRussian Academy of Sciencesul. Koroleva, 3Russia

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