Chemistry of Natural Compounds

, Volume 44, Issue 4, pp 545–547 | Cite as

Steroidal Glycosides from Allium rotundum

  • M. R. Maisashvili
  • D. K. Kuchukhidze
  • L. N. Gvazava
  • L. I. Eristavi

We have previously reported [1] the isolation of seven sapogenins from inflorescences and flower stalks of Allium rotundum (Alliaceae). Herein we present results from structural studies of five steroidal glycosides from this plant.

Exhaustive extraction of air-dried raw material with hot methanol isolated total saponins, which were separated by repeated chromatography into seven pure compounds called in order of increasing polarity glycosides 17. According to color reactions [2] and IR spectroscopy, they were spirostanols.

The structures of the glycosides were elucidated based on chemical transformations and GC, IR, mass, and NMR spectroscopy.

Exhaustive methylation of the saponins by the Hakomori method [ 3] and subsequent methanolysis gave information about the genins; GC, about the monosaccharide compositions, the presence of branching centers, and the sites of attachment of the sugar units to each other (Table  1).
Table 1

Genin Composition and GC Data for Glycosides 1, 2, 46



Glycoside Saponin Diosgenin Steroidal Glycoside Double Resonance Experiment 
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Copyright information

© Springer Science+Business Media, Inc. 2008

Authors and Affiliations

  • M. R. Maisashvili
    • 1
  • D. K. Kuchukhidze
    • 1
  • L. N. Gvazava
    • 2
  • L. I. Eristavi
    • 1
  1. 1.Tbilisi State Medical Universityul. AkhvledianiGeorgia
  2. 2.I. Kutateladze Institute of Pharmaceutical Chemistryul. P. SaradzhishviliGeorgia

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