Chemistry of Natural Compounds

, Volume 42, Issue 4, pp 400–406 | Cite as

Acidic isomerization of alantolactone derivatives

  • S. G. Klochkov
  • S. V. Afanaséva
  • A. N. Pushin


A series of derivatives of the natural sesquiterpene lactones alantolactone (1) and isoalantolactone (2) was prepared. The α-methylene-γ-lactone moiety was retained in the structures of these for further modifications using reactions that affected exclusively the nonconjugated double bonds of the decalin ring.

Key words

sesquiterpene lactones alantolactone isoalantolactone acidic isomerization Inula helenium


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • S. G. Klochkov
    • 1
  • S. V. Afanaséva
    • 1
  • A. N. Pushin
    • 1
  1. 1.Institute of Physiologically Active CompoundsRussian Academy of SciencesMoscow Region, Noginsk District, Chernogolovka

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