Chemistry of Natural Compounds

, Volume 40, Issue 5, pp 460–464 | Cite as

Two new compounds from Phyllanthus niruri

  • Wan-Xing Wei
  • Yuan-Jiang Pan
  • Hong Zhang
  • Cui-Wu lin
  • Teng-You Wei


Three compounds were isolated from Phyllanthus niruri Linn. One effective method, improved dry column liquid chromatography for isolating these compounds, was applied on a silica gel column. It is a combination of conventional dry column chromatographic and flash chromatographic techniques. Structures of those obtained compounds were elucidated by means of spectral techniques including IR, MS, and 1D NMR and 2D NMR. Compound 1 was elucidated as 2,3,5,6-tetrahydroxybenzyl acetate. Compound 2 , 2,4,5-trihydroxy-3-(4,6,7-trihydroxy-3-oxo-1,3-dihydroisobenzofuran-5-yl)-benzoic acid methyl ester, was given the name phyllangin, and compound 3 was named corilagin. Compounds 1 and 2 are new compounds.

Key words

Dry column chromatography Phyllanthus niruriLinn; 2,3,5,6-tetrahydroxybenzyl acetate Phyllangin Corilagin 


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Copyright information

© Springer Science+Business Media, Inc. 2004

Authors and Affiliations

  • Wan-Xing Wei
    • 1
  • Yuan-Jiang Pan
    • 2
  • Hong Zhang
    • 2
  • Cui-Wu lin
    • 1
  • Teng-You Wei
    • 1
  1. 1.College of Chemistry and Chemical EngineeringGuangxi UniversityNanningP. R. China;
  2. 2.Department of ChemistryZhejiang UniversityHangzhouP. R. China

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