This microreview is devoted to recently reported methods for the synthesis of 4-quinolones including activated alkyne-based reactions, K2CO3/DIPEA-catalyzed reaction, Baylis–Hillman reaction, Pd-catalyzed Buchwald–Hartwig amination, intramolecular Houben–Hoesch reaction, tandem acyl transfer – cyclization of o-alkynoylanilines, fused heterocycle synthesis via double heteroannulation, enaminone-directed C–H amidation, and formation of 4-quinolone moiety as a part of natural products. Microreview covers literature from 2013 to 2017.
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Financial support from the Research Council of the Payame Noor University is gratefully acknowleged.
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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2018, 54(6), 587–589
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Sajadikhah, S.S., Lotfifar, N. Recent methods of 4-quinolone synthesis (microreview). Chem Heterocycl Comp 54, 587–589 (2018). https://doi.org/10.1007/s10593-018-2311-1
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DOI: https://doi.org/10.1007/s10593-018-2311-1