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Chemistry of Heterocyclic Compounds

, Volume 54, Issue 3, pp 329–333 | Cite as

Zr-mediated synthesis of chiral cyclic imines and their application in Betti reactions

  • Elena Speich
  • Luca Banfi
  • Lisa Moni
  • Renata Riva
  • Valeria Rocca
  • Andrea BassoEmail author
Article

A novel synthetic strategy has been outlined to assemble enantiomerically pure Betti bases with unprecedented structures. This involves the Zr-mediated reduction of pyrrolidin-2-ones to cyclic imines and their subsequent reaction with phenolic derivatives.

Keywords

cyclic imines Schwartz reagent Betti reaction 

Notes

A. B. thanks Mr. Pietro Marchi for his contribution to this work.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Elena Speich
    • 1
  • Luca Banfi
    • 1
  • Lisa Moni
    • 1
  • Renata Riva
    • 1
  • Valeria Rocca
    • 1
  • Andrea Basso
    • 1
    Email author
  1. 1.Università degli Studi di Genova, Dipartimento di Chimica e Chimica IndustrialeGenovaItaly

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