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Chemistry of Heterocyclic Compounds

, Volume 53, Issue 12, pp 1286–1293 | Cite as

Copper(II) bromide-catalyzed conjugate addition of furans to α,β-unsaturated carbonyl compounds

  • Alexander A. Fadeev
  • Maxim G. Uchuskin
  • Igor V. Trushkov
  • Anton S. MakarovEmail author
Article

A simple method for the synthesis of 2-(3-oxoalkyl)furan derivatives based on conjugate addition of 2-substituted furans to various α,β-unsaturated carbonyl compounds in the presence of copper(II) bromide as catalyst was developed.

Keywords

copper(II) bromide furan α,β-unsaturated carbonyl compounds conjugate addition 

Notes

This work was supported by the Russian Foundation for Basic Research (grant 16-33-00101 mol_a) and the Ministry of Education and Science of the Russian Federation (contract No. 02.a03.0008).

Supplementary material

10593_2018_2206_MOESM1_ESM.pdf (4.6 mb)
ESM 1 (PDF 4738 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Alexander A. Fadeev
    • 1
  • Maxim G. Uchuskin
    • 1
    • 2
  • Igor V. Trushkov
    • 2
    • 3
  • Anton S. Makarov
    • 1
    Email author
  1. 1.Perm State National Research UniversityPermRussia
  2. 2.RUDN UniversityMoscowRussia
  3. 3.Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and ImmunologyMoscowRussia

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