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Synthesis of new pyrrolo[3,2-l]acridinones and pyrrolo[3,2-c][1,8]naphthyridinones by condensation of methoxybenzenes or phenols with isobutyric aldehyde and o-aminonitriles

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Chemistry of Heterocyclic Compounds Aims and scope

A reaction of methoxybenzenes or phenols with isobutyric aldehyde and 2-amino-5-nitro- or 2-amino-4-chlorobenzonitriles in concentrated H2SO4 medium was used for the preparation of new pyrrolo[3,2-l]acridinone derivatives. Analogous reactions using 2-amino-3-pyridinecarbonitrile enabled the synthesis of previously unknown benzo[b]pyrrolo[3,2-c][1,8]naphthyridinones.

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Authors and Affiliations

  1. Institute of Technical Chemistry, Ural Branch, Russian Academy of Sciences, 3 Akademika Koroleva St., Perm, 614013, Russia

    Yuliya S. Rozhkova, Tatyana S. Vshivkova, Vyacheslav V. Morozov, Aleksei A. Gorbunov & Yurii V. Shklyaev

  2. Perm State National Research University, 15 Bukireva St., Perm, 614990, Russia

    Vladimir E. Zhulanov & Yurii V. Shklyaev

Authors
  1. Yuliya S. Rozhkova
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  2. Tatyana S. Vshivkova
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  3. Vyacheslav V. Morozov
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  4. Vladimir E. Zhulanov
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  5. Aleksei A. Gorbunov
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  6. Yurii V. Shklyaev
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Correspondence to Yuliya S. Rozhkova.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(11), 1228–1241

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Rozhkova, Y.S., Vshivkova, T.S., Morozov, V.V. et al. Synthesis of new pyrrolo[3,2-l]acridinones and pyrrolo[3,2-c][1,8]naphthyridinones by condensation of methoxybenzenes or phenols with isobutyric aldehyde and o-aminonitriles. Chem Heterocycl Comp 53, 1228–1241 (2017). https://doi.org/10.1007/s10593-018-2195-0

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  • DOI: https://doi.org/10.1007/s10593-018-2195-0

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