This microreview considers various approaches to the synthesis of pyridine derivatives containing a tricyanobutadiene motif in their structures. The following methods for the preparation of pyridine derivatives with tricyanobutadiene motif are described: synthesis from 2-halonicotinonitriles, syntheses starting from malononitrile dimer, malononitrile, and a pseudo four-component synthesis.
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This study was supported by a grant from the Russian Science Foundation (project No.17-13-01237)
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(11), 1178–1180
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Ershov, O.V., Bardasov, I.N. Synthesis of pyridine derivatives containing a tricyanobutadiene motif (microreview). Chem Heterocycl Comp 53, 1178–1180 (2017). https://doi.org/10.1007/s10593-018-2190-5
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DOI: https://doi.org/10.1007/s10593-018-2190-5