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3,4-Dihydroquinoxalin-2-ones: recent advances in synthesis and bioactivities (microreview)

  • HETEROCYCLES IN FOCUS
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Chemistry of Heterocyclic Compounds Aims and scope

A summary of recent synthetic approaches to 3,4-dihydroquinoxalin-2-ones is discussed herein along with highlights of biological activity. The synthetic approaches include access to enantiopure 3,4-dihydroquinoxalin-2-ones from chiral pool amino acids via coupling/cyclization, Michael addition/cyclization cascades, 3,3-disubstituted systems from multicomponent couplings, Bargellini reaction, or photochemical reduction.

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Authors and Affiliations

  1. Organic Chemistry Division, Department of Chemistry, UiT The Arctic University of Norway, N-9037, Tromsø, Norway

    Tone Kristoffersen & Jørn H. Hansen

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  1. Tone Kristoffersen
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  2. Jørn H. Hansen
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Correspondence to Jørn H. Hansen.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2017, 53(3), 310–312

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Kristoffersen, T., Hansen, J.H. 3,4-Dihydroquinoxalin-2-ones: recent advances in synthesis and bioactivities (microreview). Chem Heterocycl Comp 53, 310–312 (2017). https://doi.org/10.1007/s10593-017-2052-6

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  • DOI: https://doi.org/10.1007/s10593-017-2052-6

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